Clinical development and potential of photothermal and photodynamic therapies for cancer

X Li, JF Lovell, J Yoon, X Chen - Nature reviews Clinical oncology, 2020 - nature.com
Light-activated, photosensitizer-based therapies have been established as safe modalities
of tumour ablation for numerous cancer indications. Two main approaches are available …

Liposomes: Structure, composition, types, and clinical applications

H Nsairat, D Khater, U Sayed, F Odeh, A Al Bawab… - Heliyon, 2022 - cell.com
Liposomes are now considered the most commonly used nanocarriers for various potentially
active hydrophobic and hydrophilic molecules due to their high biocompatibility …

Targeting drugs to tumours using cell membrane-coated nanoparticles

RH Fang, W Gao, L Zhang - Nature Reviews Clinical Oncology, 2023 - nature.com
Traditional cancer therapeutics, such as chemotherapies, are often limited by their non-
specific nature, causing harm to non-malignant tissues. Over the past several decades …

Nanoparticles for cancer therapy: current progress and challenges

S Gavas, S Quazi, TM Karpiński - Nanoscale research letters, 2021 - Springer
Cancer is one of the leading causes of death and morbidity with a complex pathophysiology.
Traditional cancer therapies include chemotherapy, radiation therapy, targeted therapy, and …

Cancer nanomedicine: progress, challenges and opportunities

J Shi, PW Kantoff, R Wooster, OC Farokhzad - Nature reviews cancer, 2017 - nature.com
The intrinsic limits of conventional cancer therapies prompted the development and
application of various nanotechnologies for more effective and safer cancer treatment …

The entry of nanoparticles into solid tumours

S Sindhwani, AM Syed, J Ngai, BR Kingston… - Nature materials, 2020 - nature.com
The concept of nanoparticle transport through gaps between endothelial cells (inter-
endothelial gaps) in the tumour blood vessel is a central paradigm in cancer nanomedicine …

Nanoparticles in the clinic: An update

AC Anselmo, S Mitragotri - Bioengineering & translational …, 2019 - Wiley Online Library
Nanoparticle drug delivery systems have been used in the clinic since the early 1990's.
Since that time, the field of nanomedicine has evolved alongside growing technological …

Progressing nanotechnology to improve targeted cancer treatment: overcoming hurdles in its clinical implementation

M Chehelgerdi, M Chehelgerdi, OQB Allela… - Molecular cancer, 2023 - Springer
The use of nanotechnology has the potential to revolutionize the detection and treatment of
cancer. Developments in protein engineering and materials science have led to the …

Designing hydrogels for controlled drug delivery

J Li, DJ Mooney - Nature Reviews Materials, 2016 - nature.com
Hydrogel delivery systems can leverage therapeutically beneficial outcomes of drug delivery
and have found clinical use. Hydrogels can provide spatial and temporal control over the …

Analysis of nanoparticle delivery to tumours

S Wilhelm, AJ Tavares, Q Dai, S Ohta, J Audet… - Nature reviews …, 2016 - nature.com
Targeting nanoparticles to malignant tissues for improved diagnosis and therapy is a
popular concept. However, after surveying the literature from the past 10 years, only …