Uniform manifold approximation and projection (UMAP) has been rapidly adopted by the
population genetics community to study population structure. It has become common in …

Proposed genetic approaches for reducing human malaria include population modification,
which introduces genes into vector mosquitoes to reduce or prevent parasite transmission …

Highlights•Long-distance dispersal underlies the global threat of mosquito disease•Long-
distance dispersal and active flight should be analysed as distinct processes•Insecticide …

Simulation is a key tool in population genetics for both methods development and empirical
research, but producing simulations that recapitulate the main features of genomic datasets …

Dimensionality reduction is a common tool for visualization and inference of population
structure from genotypes, but popular methods either return too many dimensions for easy …

Resistance to pyrethroid insecticides is a major concern for malaria vector control.
Pyrethroids target the voltage‐gated sodium channel (VGSC), an essential component of the …

The two main Afrotropical malaria vectors-Anopheles coluzzii and An. gambiae–are
genetically distinct and reproductively isolated across West Africa. However, populations at …

CRISPR-based homing gene drives can be designed to disrupt essential genes whilst
biasing their own inheritance, leading to suppression of mosquito populations in the …

Synthetic gene drive constructs could, in principle, provide the basis for highly efficient
interventions to control disease vectors and other pest species. This efficiency derives in part …

Abstract The Democratic Republic of Congo (DRC) suffers from one of the highest malaria
burdens worldwide, but information on its Anopheles vector populations is relatively limited …