The multifaceted nature of antimicrobial peptides: Current synthetic chemistry approaches and future directions
Bacterial infections caused by 'superbugs' are increasing globally, and conventional
antibiotics are becoming less effective against these bacteria, such that we risk entering a …
antibiotics are becoming less effective against these bacteria, such that we risk entering a …
Antimicrobial and cell-penetrating peptides: understanding penetration for the design of novel conjugate antibiotics
A Hadjicharalambous, N Bournakas, H Newman… - Antibiotics, 2022 - mdpi.com
Antimicrobial peptides (AMPs) are short oligopeptides that can penetrate the bacterial inner
and outer membranes. Together with cell-penetrating peptides (CPPs), they are called …
and outer membranes. Together with cell-penetrating peptides (CPPs), they are called …
No country for old antibiotics! Antimicrobial peptides (AMPs) as next-generation treatment for skin and soft tissue infection
In recent years, the unprecedented rise of bacterial antibiotic resistance together with the
lack of adequate therapies have made the treatment of skin infections and chronic wounds …
lack of adequate therapies have made the treatment of skin infections and chronic wounds …
Recent advances in Staphylococcus aureus infection: focus on vaccine development
Staphylococcus aureus normally colonizes the nasal cavity and pharynx. After breaching the
normal habitat, the organism is able to cause a number of infections at any site of the body …
normal habitat, the organism is able to cause a number of infections at any site of the body …
Peptide–Drug Conjugates: An Emerging Direction for the Next Generation of Peptide Therapeutics
Building on recent advances in peptide science, medicinal chemists have developed a
hybrid class of bioconjugates, called peptide–drug conjugates, that demonstrate improved …
hybrid class of bioconjugates, called peptide–drug conjugates, that demonstrate improved …
Antimicrobial and amyloidogenic activity of peptides. Can antimicrobial peptides be used against SARS-CoV-2?
SR Kurpe, SY Grishin, AK Surin, AV Panfilov… - International Journal of …, 2020 - mdpi.com
At present, much attention is paid to the use of antimicrobial peptides (AMPs) of natural and
artificial origin to combat pathogens. AMPs have several points that determine their …
artificial origin to combat pathogens. AMPs have several points that determine their …