The multifaceted nature of antimicrobial peptides: Current synthetic chemistry approaches and future directions

BH Gan, J Gaynord, SM Rowe, T Deingruber… - Chemical Society …, 2021 - pubs.rsc.org
Bacterial infections caused by 'superbugs' are increasing globally, and conventional
antibiotics are becoming less effective against these bacteria, such that we risk entering a …

Antimicrobial and cell-penetrating peptides: understanding penetration for the design of novel conjugate antibiotics

A Hadjicharalambous, N Bournakas, H Newman… - Antibiotics, 2022 - mdpi.com
Antimicrobial peptides (AMPs) are short oligopeptides that can penetrate the bacterial inner
and outer membranes. Together with cell-penetrating peptides (CPPs), they are called …

No country for old antibiotics! Antimicrobial peptides (AMPs) as next-generation treatment for skin and soft tissue infection

M Răileanu, R Borlan, A Campu, L Janosi… - International Journal of …, 2023 - Elsevier
In recent years, the unprecedented rise of bacterial antibiotic resistance together with the
lack of adequate therapies have made the treatment of skin infections and chronic wounds …

Recent advances in Staphylococcus aureus infection: focus on vaccine development

S Ansari, RK Jha, SK Mishra, BR Tiwari… - Infection and drug …, 2019 - Taylor & Francis
Staphylococcus aureus normally colonizes the nasal cavity and pharynx. After breaching the
normal habitat, the organism is able to cause a number of infections at any site of the body …

Peptide–Drug Conjugates: An Emerging Direction for the Next Generation of Peptide Therapeutics

TT Dean, J Jelú-Reyes, ALC Allen… - Journal of Medicinal …, 2024 - ACS Publications
Building on recent advances in peptide science, medicinal chemists have developed a
hybrid class of bioconjugates, called peptide–drug conjugates, that demonstrate improved …

Antimicrobial and amyloidogenic activity of peptides. Can antimicrobial peptides be used against SARS-CoV-2?

SR Kurpe, SY Grishin, AK Surin, AV Panfilov… - International Journal of …, 2020 - mdpi.com
At present, much attention is paid to the use of antimicrobial peptides (AMPs) of natural and
artificial origin to combat pathogens. AMPs have several points that determine their …