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Important roles of dietary taurine, creatine, carnosine, anserine and 4-hydroxyproline in human nutrition and health
G Wu - Amino acids, 2020 - Springer
Taurine (a sulfur-containing β-amino acid), creatine (a metabolite of arginine, glycine and
methionine), carnosine (a dipeptide; β-alanyl-l-histidine), and 4-hydroxyproline (an imino …
methionine), carnosine (a dipeptide; β-alanyl-l-histidine), and 4-hydroxyproline (an imino …
[HTML][HTML] Amino acids in the regulation of aging and aging-related diseases
CA Canfield, PC Bradshaw - Translational Medicine of Aging, 2019 - Elsevier
Amino acids are the building blocks of protein, but also play important cellular signaling
roles. The mechanisms through which altered levels of many amino acids are sensed and …
roles. The mechanisms through which altered levels of many amino acids are sensed and …
[HTML][HTML] Peptide based therapeutics and their use for the treatment of neurodegenerative and other diseases
MH Baig, K Ahmad, M Saeed, AM Alharbi… - Biomedicine & …, 2018 - Elsevier
Bioactive peptides are actively involved in different biological functions and importantly
contribute to human health, and the use of peptides as therapeutics has a long successful …
contribute to human health, and the use of peptides as therapeutics has a long successful …
A comprehensive review on source, types, effects, nanotechnology, detection, and therapeutic management of reactive carbonyl species associated with various …
S Fuloria, V Subramaniyan, S Karupiah, U Kumari… - Antioxidants, 2020 - mdpi.com
Continuous oxidation of carbohydrates, lipids, and amino acids generate extremely reactive
carbonyl species (RCS). Human body comprises some important RCS namely hexanal …
carbonyl species (RCS). Human body comprises some important RCS namely hexanal …
Pivotal role of carnosine in the modulation of brain cells activity: Multimodal mechanism of action and therapeutic potential in neurodegenerative disorders
G Caruso, F Caraci, RB Jolivet - Progress in neurobiology, 2019 - Elsevier
Abstract Carnosine (β-alanyl-l-histidine), a dipeptide, is an endogenous antioxidant widely
distributed in excitable tissues like muscles and the brain. Although discovered more than a …
distributed in excitable tissues like muscles and the brain. Although discovered more than a …
[HTML][HTML] Carbonic anhydrase activators for neurodegeneration: an overview
V Poggetti, S Salerno, E Baglini, E Barresi… - Molecules, 2022 - mdpi.com
Carbonic anhydrases (CAs) are a family of ubiquitous metal enzymes catalyzing the
reversible conversion of CO2 and H2O to HCO3− with the release of a proton. They play an …
reversible conversion of CO2 and H2O to HCO3− with the release of a proton. They play an …
The role and mechanisms of gut microbiota in diabetic nephropathy, diabetic retinopathy and cardiovascular diseases
Q Lv, Z Li, A Sui, X Yang, Y Han, R Yao - Frontiers in Microbiology, 2022 - frontiersin.org
Type 2 diabetes mellitus (T2DM) and T2DM-related complications [such as retinopathy,
nephropathy, and cardiovascular diseases (CVDs)] are the most prevalent metabolic …
nephropathy, and cardiovascular diseases (CVDs)] are the most prevalent metabolic …
Therapeutic potential of carnosine and its derivatives in the treatment of human diseases
K Chmielewska, K Dzierzbicka… - Chemical Research …, 2020 - ACS Publications
Despite significant progress in the pathogenesis, diagnosis, treatment, and prevention of
cancer and neurodegenerative diseases, their occurrence and mortality are still high around …
cancer and neurodegenerative diseases, their occurrence and mortality are still high around …
Fatty acids, antioxidants and physical activity in brain aging
HR Freitas, GC Ferreira, IH Trevenzoli, KJ Oliveira… - Nutrients, 2017 - mdpi.com
Polyunsaturated fatty acids and antioxidants are important mediators in the central nervous
system. Lipid derivatives may control the production of proinflammatory agents and regulate …
system. Lipid derivatives may control the production of proinflammatory agents and regulate …
The clinical pharmacology of non-sedating antihistamines
K Yanai, T Yoshikawa, A Yanai, T Nakamura… - Pharmacology & …, 2017 - Elsevier
We previously reported on brain H 1 receptor occupancy measurements of antihistamines in
human brain using [11 C] doxepin and positron emission tomography (PET). We proposed …
human brain using [11 C] doxepin and positron emission tomography (PET). We proposed …