[HTML][HTML] Silk fibroin-based hydrogels for cartilage organoids in osteoarthritis treatment

C Shen, Z Zhou, R Li, S Yang, D Zhou, F Zhou… - …, 2025 - pmc.ncbi.nlm.nih.gov
Osteoarthritis (OA) is a common joint disease characterized by cartilage degeneration. It can
cause severe pain, deformity and even amputation risk. However, existing clinical treatment …

Elastin‐like recombinamers: deconstructing and recapitulating the functionality of Extracellular Matrix proteins using recombinant protein polymers

S Acosta, L Quintanilla‐Sierra, L Mbundi… - Advanced Functional …, 2020 - Wiley Online Library
In the development of tissue engineering strategies to replace, remodel, regenerate, or
support damaged tissue, the development of bioinspired biomaterials that recapitulate the …

Phospholipid‐induced silk fibroin hydrogels and their potential as cell carriers for tissue regeneration

C Laomeephol, M Guedes, H Ferreira… - Journal of Tissue …, 2020 - Wiley Online Library
Silk fibroin (SF) hydrogels can be obtained via self‐assembly, but this process takes several
days or weeks, being unfeasible to produce cell carrier hydrogels. In this work, a …

Strategies in regenerative medicine for intervertebral disc repair using mesenchymal stem cells and bioscaffolds

J Melrose - Regenerative medicine, 2016 - Taylor & Francis
The intervertebral disc (IVD) is a major weight bearing structure that undergoes
degenerative changes with aging limiting its ability to dissipate axial spinal loading in an …

The elastin matrix in tissue engineering and regeneration

GC Yeo, SM Mithieux, AS Weiss - Current Opinion in Biomedical …, 2018 - Elsevier
The elastin matrix crucially confers mechanical strength, elasticity, organization and
biological signaling to almost all connective tissues, which are matched to specific tissue …

Reloadable silk-hydrogel hybrid scaffolds for sustained and targeted delivery of molecules

SK Singh, BK Bhunia, N Bhardwaj… - Molecular …, 2016 - ACS Publications
Tunable repeated drug administration is often inevitable in a number of pathological cases.
Reloadable 3D matrices for sustained drug delivery are predicted as a prospective avenue …

Enhancing the carboxylation efficiency of silk fibroin through the disruption of noncovalent interactions

DL Heichel, KA Burke - Bioconjugate Chemistry, 2020 - ACS Publications
Silk fibroin is a semicrystalline protein used as a renewable polymer source and as a
biomaterial platform, but existing methods to synthetically modify fibroin suffer from low …

Elastin-like recombinamers: Deconstructing and recapitulating the functionality of extracellular matrix proteins using recombinant protein polymers

S Acosta Rodríguez, L Quintanilla Sierra, L Mbundi… - 2020 - uvadoc.uva.es
In the development of tissue engineering strategies to replace, remodel, regenerate, or
support damaged tissue, the development of bioinspired biomaterials that recapitulate the …

Research progress on the effect of surface charge of biomaterials on bone formation

S Wang, D Song, C Qiao - Sheng wu yi xue Gong Cheng xue za zhi …, 2021 - europepmc.org
随着材料学, 生物学领域研究的不断进步, 集合材料学和生物学双重特性的生物材料的重要性
日益凸显. 目前生物材料在组织工程, 制药工程和再生医学等领域应用较为广泛. 在因外伤 …

生物材料表面电荷影响骨形成作用的研究进展

绍泰王, 东升宋, 春燕乔 - Sheng Wu Yi Xue Gong Cheng Xue …, 2021 - pmc.ncbi.nlm.nih.gov
随着材料学, 生物学领域研究的不断进步, 集合材料学和生物学双重特性的生物材料的重要性
日益凸显. 目前生物材料在组织工程, 制药工程和再生医学等领域应用较为广泛. 在因外伤 …