Neoadjuvant immune checkpoint blockade: a window of opportunity to advance cancer immunotherapy

SL Topalian, PM Forde, LA Emens, M Yarchoan… - Cancer cell, 2023 - cell.com
Among new treatment approaches for patients with cancer, few have accelerated as quickly
as neoadjuvant immune checkpoint blockade (ICB). Neoadjuvant cancer therapy is …

Immune-checkpoint inhibition for resectable non-small-cell lung cancer—Opportunities and challenges

G Mountzios, J Remon, LEL Hendriks… - Nature Reviews …, 2023 - nature.com
Therapeutic strategies harnessing the immune system to eliminate tumour cells have been
successfully used for several cancer types, including in patients with advanced-stage non …

Challenges and controversies in resectable non-small cell lung cancer: a clinician's perspective

I Houda, C Dickhoff, CA Uyl-de Groot… - The Lancet Regional …, 2024 - thelancet.com
The treatment landscape of resectable early-stage non-small cell lung cancer (NSCLC) is
transforming due to the approval of novel adjuvant and neoadjuvant systemic treatments …

The American Association for Thoracic Surgery (AATS) 2023 Expert Consensus Document: staging and multidisciplinary management of patients with early-stage non …

EC Panel, B Kidane, M Bott, J Spicer, L Backhus… - The Journal of thoracic …, 2023 - Elsevier
The American Association for Thoracic Surgery (AATS) 2023 Expert Consensus Document:
Staging and multidisciplinary management of patients with early-stage non–small cell lung …

[HTML][HTML] Perioperative treatment strategies in EGFR-mutant early-stage NSCLC: current evidence and future challenges

J Remon, SPL Saw, F Cortiula, PK Singh… - Journal of Thoracic …, 2024 - Elsevier
Abstract Treatment with 3 years of adjuvant osimertinib is considered a new standard in
patients with completely resected stage I to IIIA NSCLC harboring a common sensitizing …

Association between surgical quality metric adherence and overall survival among US veterans with early-stage non–small cell lung cancer

BT Heiden, DB Eaton, SH Chang, Y Yan… - JAMA …, 2023 - jamanetwork.com
Importance Surgical resection remains the preferred treatment for functionally fit patients
diagnosed with early-stage non–small cell lung cancer (NSCLC). Process-based …

Moving Immunotherapy Into the Treatment of Resectable Non–Small Cell Lung Cancer

JE Chaft, R Dziadziuszko… - American Society of …, 2024 - ascopubs.org
Clinical investigation of immune checkpoint inhibitors (ICIs) has expanded from indications
in metastatic non–small cell lung cancer (NSCLC) to add to the treatment of early-stage or …

Perioperative therapy for resectable non–small-cell lung cancer: Weighing Options for the present and future

D Uprety, HJ West - JCO Oncology Practice, 2023 - ascopubs.org
Anatomic surgical resection followed by cisplatin-based platinum-doublet adjuvant
chemotherapy has been a long-standing standard of care for patients with early-stage …

[HTML][HTML] Underutilization of systemic therapy in patients with NSCLC undergoing pneumonectomy: a missed opportunity for survival

JH Rodriguez-Quintero, MK Kamel, G Dawodu… - JTO Clinical and …, 2023 - Elsevier
Introduction Recent trials have reported promising results with the addition of
immunotherapy to chemotherapy for patients with locally advanced NSCLC, but in practice …

Expert consensus on perioperative treatment for non-small cell lung cancer

J Duan, F Tan, N Bi, C Chen, KN Chen… - Translational lung …, 2022 - pmc.ncbi.nlm.nih.gov
Background Non-small cell lung cancer (NSCLC) accounts for 85% of all newly diagnosed
lung cancer cases. Among patients with NSCLC, about 20% are diagnosed with stage I and …