The short-term and long-term adverse effects of melatonin treatment in children and adolescents: a systematic review and GRADE assessment

MN Händel, HK Andersen, A Ussing, A Virring… - …, 2023 - thelancet.com
Background Currently, melatonin is used to treat children and adolescents with insomnia
without knowing the full extent of the short-term and long-term consequences. Our aim was …

Use of melatonin in children and adolescents with idiopathic chronic insomnia: a systematic review, meta-analysis, and clinical recommendation

H Edemann-Callesen, HK Andersen, A Ussing… - …, 2023 - thelancet.com
Background Melatonin prescriptions for children and adolescents have increased
substantially during the last decade. Existing clinical recommendations focus on melatonin …

Use of melatonin for children and adolescents with chronic insomnia attributable to disorders beyond indication: a systematic review, meta-analysis and clinical …

H Edemann-Callesen, HK Andersen, A Ussing… - …, 2023 - thelancet.com
Background Melatonin has become a widely used slee** aid for young individuals
currently not included in existing guidelines. The aim was to develop a recommendation on …

Psychotropic drug use among children and adolescents in the Nordic countries: a systematic review

DR Ollerup, L Rasmussen, SL Elkrog… - European Child & …, 2024 - Springer
The Nordic countries have rather homogenous populations and similar health care systems,
and one could therefore expect comparable levels of psychopathology and psychotropic …

Use of benzodiazepines and benzodiazepine‐related drugs in the Nordic countries between 2000 and 2020

M Højlund, LS Gudmundsson… - Basic & Clinical …, 2023 - Wiley Online Library
Use of benzodiazepines (BZ) and related drugs is subject to considerable debate due to
problems with dependency and adverse events. We aimed to describe and compare their …

Melatonin use among children, adolescents, and young adults: a Danish nationwide drug utilization study

M Bliddal, H Kildegaard, L Rasmussen, M Ernst… - European Child & …, 2023 - Springer
We aimed to provide a detailed description of the use of melatonin in Danish children,
adolescents, and young adults during 2012–2019. We identified melatonin users 0–24 …

Killing pain?: a population-based registry study of the use of prescription analgesics, anxiolytics, and hypnotics among all children, adolescents and young adults in …

H Stangeland, M Handal, SO Skurtveit… - European Child & …, 2023 - Springer
The ongoing opioid epidemic has been a global concern for years, increasingly due to its
heavy toll on young people's lives and prospects. Few studies have investigated trends in …

The role of supplements and over-the-counter products to improve sleep in children: A systematic review

A Innocenti, G Lentini, S Rapacchietta… - International Journal of …, 2023 - mdpi.com
The sleep–wake cycle is a complex multifactorial process involving several
neurotransmitters, including acetylcholine, norepinephrine, serotonin, histamine, dopamine …

Adverse events in long-term studies of exogenous melatonin

FMC Besag, MJ Vasey - Expert Opinion on Drug Safety, 2022 - Taylor & Francis
Introduction Exogenous melatonin is regulated as a drug in the UK and EU but is available
as an over-the-counter dietary supplement in the US and Canada. In the last 15 years …

Trends in use of attention deficit hyperactivity disorder medication among children and adolescents in Scandinavia in 2010–2020

AMS Sørensen, R Wesselhöeft, JH Andersen… - European Child & …, 2023 - Springer
The objective of the study was to compare the use of attention deficit hyperactivity disorder
(ADHD) medication among children and adolescents in Scandinavia 2010–2020. Using …