Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals
Almost 25 centuries ago, Hippocrates, the father of medicine, proclaimed “Let food be thy
medicine and medicine be thy food.” Exploring the association between diet and health …
medicine and medicine be thy food.” Exploring the association between diet and health …
Piano stool Ru (II)-arene complexes having three monodentate legs: A comprehensive review on their development as anticancer therapeutics over the past decade
The popularity of RAPTA-C in in vivo studies has steered the way for complexes of the type
[Ru (η 6-arene)(X)(Y)(Z)] n+ (where X, Y and Z are monodentate ligands) to be developed …
[Ru (η 6-arene)(X)(Y)(Z)] n+ (where X, Y and Z are monodentate ligands) to be developed …
Perspectives on medicinal properties of plumbagin and its analogs
Plumbagin is one of the simplest plant secondary metabolite of three major phylogenic
families viz. Plumbaginaceae, Droseraceae, and Ebenceae, and exhibits highly potent …
families viz. Plumbaginaceae, Droseraceae, and Ebenceae, and exhibits highly potent …
Noteworthy secondary metabolites naphthoquinones-their occurrence, pharmacological properties and analysis
P Babula, V Adam, L Havel… - Current Pharmaceutical …, 2009 - ingentaconnect.com
Chemical investigation of many bacterial and fungal, as well as plant species has revealed
the presence of interesting compounds derived from naphthalene-1, 4-naphthoquinones …
the presence of interesting compounds derived from naphthalene-1, 4-naphthoquinones …
Emerging role of plumbagin: Cytotoxic potential and pharmaceutical relevance towards cancer therapy
Plumbagin is a naphthoquinone derived yellow crystalline phytochemical. Plumbagin has a
wide range of biological effects including cytotoxicity against cancer cells both in vitro and in …
wide range of biological effects including cytotoxicity against cancer cells both in vitro and in …
Plumbagin: a potential anti-cancer compound
A Roy - Mini reviews in medicinal chemistry, 2021 - ingentaconnect.com
Cancer is a deadly disease, which has significantly increased in both developed and
develo** nations. Treatment of cancer utilizing radiotherapy or chemotherapy actuates a …
develo** nations. Treatment of cancer utilizing radiotherapy or chemotherapy actuates a …
Inhibition of MDA‐MB‐231 breast cancer cell proliferation and tumor growth by apigenin through induction of G2/M arrest and histone H3 acetylation‐mediated …
TH Tseng, MH Chien, WL Lin, YC Wen… - Environmental …, 2017 - Wiley Online Library
ABSTRACT Apigenin (4′, 5, 7‐trihydroxyflavone), a flavonoid commonly found in fruits and
vegetables, has anticancer properties in various malignant cancer cells. However, the …
vegetables, has anticancer properties in various malignant cancer cells. However, the …
Plumbagin induces apoptotic and autophagic cell death through inhibition of the PI3K/Akt/mTOR pathway in human non-small cell lung cancer cells
YC Li, SM He, ZX He, M Li, Y Yang, JX Pang, X Zhang… - Cancer Letters, 2014 - Elsevier
Plumbagin (PLB) has shown anti-cancer activity but the mechanism is unclear. This study
has found that PLB has a potent pro-apoptotic and pro-autophagic effect on A549 and H23 …
has found that PLB has a potent pro-apoptotic and pro-autophagic effect on A549 and H23 …
Quinones derived from plant secondary metabolites as anti-cancer agents
Quinones are plant-derived secondary metabolites that present some anti-proliferation and
anti-metastasis effects in various cancer types both in vitro and in vivo. This review focuses …
anti-metastasis effects in various cancer types both in vitro and in vivo. This review focuses …
Inhibition effects of quinones on aldose reductase: antidiabetic properties
Diabetes mellitus is a chronic metabolic disease characterized by abnormal glucose
metabolism. Aldose reductase (AR) is the first enzyme in the polyol pathway and converts …
metabolism. Aldose reductase (AR) is the first enzyme in the polyol pathway and converts …