Nitric oxide signalling in cardiovascular health and disease
Nitric oxide (NO) signalling has pleiotropic roles in biology and a crucial function in
cardiovascular homeostasis. Tremendous knowledge has been accumulated on the …
cardiovascular homeostasis. Tremendous knowledge has been accumulated on the …
The autonomic nervous system and cardiac arrhythmias: current concepts and emerging therapies
Research into cardiac autonomic control has received great interest in the past 20 years,
and we are now at a critical juncture with regard to the clinical translation of the experimental …
and we are now at a critical juncture with regard to the clinical translation of the experimental …
The intrinsic cardiac nervous system and its role in cardiac pacemaking and conduction
The cardiac autonomic nervous system (CANS) plays a key role for the regulation of cardiac
activity with its dysregulation being involved in various heart diseases, such as cardiac …
activity with its dysregulation being involved in various heart diseases, such as cardiac …
Myths and realities of the cardiac vagus
JH Coote - The Journal of physiology, 2013 - Wiley Online Library
There is continuing belief that cardiac parasympathetic postganglionic fibres are sparse or
absent from the ventricles. This review of the literature shows that the supposition is a myth …
absent from the ventricles. This review of the literature shows that the supposition is a myth …
Mortality, cardiac vagal control and physical training–what's the link?
AN Buch, JH Coote, JN Townend - Experimental physiology, 2002 - cambridge.org
The role of the autonomic nervous system. The mechanisms by which physical training
exerts its beneficial effects on mortality and cardiovascular disease are surprisingly ill …
exerts its beneficial effects on mortality and cardiovascular disease are surprisingly ill …
Molecular and cellular neurocardiology: development, and cellular and molecular adaptations to heart disease
BA Habecker, ME Anderson, SJ Birren… - The Journal of …, 2016 - Wiley Online Library
The nervous system and cardiovascular system develop in concert and are functionally
interconnected in both health and disease. This white paper focuses on the cellular and …
interconnected in both health and disease. This white paper focuses on the cellular and …
Localization of multiple neurotransmitters in surgically derived specimens of human atrial ganglia
Dysfunction of the intrinsic cardiac nervous system is implicated in the genesis of atrial and
ventricular arrhythmias. While this system has been studied extensively in animal models …
ventricular arrhythmias. While this system has been studied extensively in animal models …
Mechanisms underlying the autonomic modulation of ventricular fibrillation initiation—tentative prophylactic properties of vagus nerve stimulation on malignant …
KE Brack, J Winter, GA Ng - Heart failure reviews, 2013 - Springer
Classical physiology teaches that vagal post-ganglionic nerves modulate the heart via
acetylcholine acting at muscarinic receptors, whilst it is accepted that vagus nerve …
acetylcholine acting at muscarinic receptors, whilst it is accepted that vagus nerve …
Nitric oxide‐cGMP pathway facilitates acetylcholine release and bradycardia during vagal nerve stimulation in the guinea‐pig in vitro
1 We tested the hypothesis that nitric oxide (NO) augments vagal neurotransmission and
bradycardia via phosphorylation of presynaptic calcium channels to increase vesicular …
bradycardia via phosphorylation of presynaptic calcium channels to increase vesicular …
Nitric oxide and autonomic control of heart rate: a question of specificity
Despite its highly diffusible nature, the gaseous signalling molecule nitric oxide (NO) can
exert specific effects within the CNS and PNS. To date, the specificity of the actions of NO …
exert specific effects within the CNS and PNS. To date, the specificity of the actions of NO …