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Light: a magical tool for controlled drug delivery
Light is a particularly appealing tool for on‐demand drug delivery due to its noninvasive
nature, ease of application, and exquisite temporal and spatial control. Great progress is …
nature, ease of application, and exquisite temporal and spatial control. Great progress is …
Reactive oxygen species-upregulating nanomedicines towards enhanced cancer therapy
Y Ding, Q Pan, W Gao, Y Pu, K Luo, B He - Biomaterials Science, 2023 - pubs.rsc.org
Reactive oxygen species (ROS) play a crucial role in physiological and pathological
processes, emerging as a therapeutic target in cancer. Owing to the high concentration of …
processes, emerging as a therapeutic target in cancer. Owing to the high concentration of …
Controllable hypoxia-activated chemotherapy as a dual enhancer for synergistic cancer photodynamic immunotherapy
M Wang, M He, M Zhang, S Xue, T Xu, Y Zhao, D Li… - Biomaterials, 2023 - Elsevier
The efficacy of photodynamic therapy (PDT) is severely limited by the hypoxic tumor
microenvironment (TME), while the performance of PDT-aroused antitumor immunity is …
microenvironment (TME), while the performance of PDT-aroused antitumor immunity is …
Smart materials for drug delivery and cancer therapy
Y Yang, W Zeng, P Huang, X Zeng, L Mei - View, 2021 - Wiley Online Library
Until now, enormous smart materials have been engineered with endogenous stimulators
such as pH, reactive oxygen species, glutathione, hypoxia and enzyme, or exogenous …
such as pH, reactive oxygen species, glutathione, hypoxia and enzyme, or exogenous …
Targeting drug delivery with light: A highly focused approach
Light is a uniquely powerful tool for controlling molecular events in biology. No other
external input (eg, heat, ultrasound, magnetic field) can be so tightly focused or so highly …
external input (eg, heat, ultrasound, magnetic field) can be so tightly focused or so highly …
Photodynamic‐chemodynamic cascade reactions for efficient drug delivery and enhanced combination therapy
Nanomedicines with photodynamic therapy and reactive oxygen species (ROS)‐triggered
drug release capabilities are promising for cancer therapy. However, most of the …
drug release capabilities are promising for cancer therapy. However, most of the …
[HTML][HTML] Utilization of polymer-lipid hybrid nanoparticles for targeted anti-cancer therapy
Cancer represents one of the most dangerous diseases, with 1.8 million deaths worldwide.
Despite remarkable advances in conventional therapies, these treatments are not effective …
Despite remarkable advances in conventional therapies, these treatments are not effective …
Near-infrared photoresponsive drug delivery nanosystems for cancer photo-chemotherapy
X Wang, Z Xuan, X Zhu, H Sun, J Li, Z **e - Journal of nanobiotechnology, 2020 - Springer
Drug delivery systems (DDSs) based on nanomaterials have shown a promise for cancer
chemotherapy; however, it remains a great challenge to localize on-demand release of …
chemotherapy; however, it remains a great challenge to localize on-demand release of …
Reactive oxygen species-sensitive polymeric nanocarriers for synergistic cancer therapy
Z Cao, D Li, J Wang, X Yang - Acta biomaterialia, 2021 - Elsevier
Reactive oxygen species (ROS)-responsive nanocarriers have aroused widespread interest
in recent years. On the one hand, a high ROS level has been detected in many types of …
in recent years. On the one hand, a high ROS level has been detected in many types of …
[HTML][HTML] Recent advances in nanomicelles delivery systems
The efficient and selective delivery of therapeutic drugs to the target site remains the main
obstacle in the development of new drugs and therapeutic interventions. Up until today …
obstacle in the development of new drugs and therapeutic interventions. Up until today …