Exploring the past and the future of protein evolution with ancestral sequence reconstruction: the 'retro'approach to protein engineering

Y Gumulya, EMJ Gillam - Biochemical Journal, 2017 - portlandpress.com
A central goal in molecular evolution is to understand the ways in which genes and proteins
evolve in response to changing environments. In the absence of intact DNA from fossils …

Forensic genetics and genomics: Much more than just a human affair

M Arenas, F Pereira, M Oliveira, N Pinto… - PLoS …, 2017 - journals.plos.org
While traditional forensic genetics has been oriented towards using human DNA in criminal
investigation and civil court cases, it currently presents a much wider application range …

PhylomeDB v4: zooming into the plurality of evolutionary histories of a genome

J Huerta-Cepas, S Capella-Gutierrez… - Nucleic acids …, 2014 - academic.oup.com
Phylogenetic trees representing the evolutionary relationships of homologous genes are the
entry point for many evolutionary analyses. For instance, the use of a phylogenetic tree can …

M1CR0B1AL1Z3R—a user-friendly web server for the analysis of large-scale microbial genomics data

O Avram, D Rapoport, S Portugez… - Nucleic acids …, 2019 - academic.oup.com
Large-scale mining and analysis of bacterial datasets contribute to the comprehensive
characterization of complex microbial dynamics within a microbiome and among different …

Tangled up in two: a burst of genome duplications at the end of the Cretaceous and the consequences for plant evolution

K Vanneste, S Maere… - … Transactions of the …, 2014 - royalsocietypublishing.org
Genome sequencing has demonstrated that besides frequent small-scale duplications, large-
scale duplication events such as whole genome duplications (WGDs) are found on many …

An investigation of irreproducibility in maximum likelihood phylogenetic inference

XX Shen, Y Li, CT Hittinger, X Chen, A Rokas - Nature communications, 2020 - nature.com
Phylogenetic trees are essential for studying biology, but their reproducibility under identical
parameter settings remains unexplored. Here, we find that 3515 (18.11%) IQ-TREE-inferred …

Dissecting incongruence between concatenation-and quartet-based approaches in phylogenomic data

XX Shen, JL Steenwyk, A Rokas - Systematic Biology, 2021 - academic.oup.com
Topological conflict or incongruence is widespread in phylogenomic data. Concatenation-
and coalescent-based approaches often result in incongruent topologies, but the causes of …

High-throughput sequencing (HTS) for the analysis of viral populations

M Pérez-Losada, M Arenas, JC Galán… - Infection, Genetics and …, 2020 - Elsevier
Abstract The development of High-Throughput Sequencing (HTS) technologies is having a
major impact on the genomic analysis of viral populations. Current HTS platforms can …

Phylogenomic systematics of ostariophysan fishes: ultraconserved elements support the surprising non-monophyly of characiformes

P Chakrabarty, BC Faircloth, F Alda, WB Ludt… - Systematic …, 2017 - academic.oup.com
Ostariophysi is a superorder of bony fishes including more than 10,300 species in 1100
genera and 70 families. This superorder is traditionally divided into five major groups …

The evolution of functional complexity within the β-amylase gene family in land plants

M Thalmann, M Coiro, T Meier, T Wicker… - BMC evolutionary …, 2019 - Springer
Abstract Background β-Amylases (BAMs) are a multigene family of glucan hydrolytic
enzymes playing a key role not only for plant biology but also for many industrial …