Dendritic cells revisited
Dendritic cells (DCs) possess the ability to integrate information about their environment and
communicate it to other leukocytes, sha** adaptive and innate immunity. Over the years, a …
communicate it to other leukocytes, sha** adaptive and innate immunity. Over the years, a …
Dendritic cell subsets and locations
S Balan, M Saxena, N Bhardwaj - International review of cell and molecular …, 2019 - Elsevier
Dendritic cells (DCs) are a unique class of immune cells that act as a bridge between innate
and adaptive immunity. The discovery of DCs by Cohen and Steinman in 1973 laid the …
and adaptive immunity. The discovery of DCs by Cohen and Steinman in 1973 laid the …
Cross-presentation by dendritic cells
OP Joffre, E Segura, A Savina… - Nature Reviews …, 2012 - nature.com
The presentation of exogenous antigens on MHC class I molecules, known as cross-
presentation, is essential for the initiation of CD8+ T cell responses. In vivo, cross …
presentation, is essential for the initiation of CD8+ T cell responses. In vivo, cross …
The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting
Dendritic cells (DCs) form a remarkable cellular network that shapes adaptive immune
responses according to peripheral cues. After four decades of research, we now know that …
responses according to peripheral cues. After four decades of research, we now know that …
Human dendritic cell subsets
Dendritic cells are highly adapted to their role of presenting antigen and directing immune
responses. Developmental studies indicate that DCs originate independently from …
responses. Developmental studies indicate that DCs originate independently from …
Dendritic cell maturation: functional specialization through signaling specificity and transcriptional programming
Dendritic cells (DC) are key regulators of both protective immune responses and tolerance
to self‐antigens. Soon after their discovery in lymphoid tissues by Steinman and Cohn, as …
to self‐antigens. Soon after their discovery in lymphoid tissues by Steinman and Cohn, as …
Dendritic cell subsets
Dendritic cells (DC) are professional antigen presenting cells comprising a variety of
subsets, as either resident or migrating cells, in lymphoid and non-lymphoid organs. In the …
subsets, as either resident or migrating cells, in lymphoid and non-lymphoid organs. In the …
Zbtb46 expression distinguishes classical dendritic cells and their committed progenitors from other immune lineages
Distinguishing dendritic cells (DCs) from other cells of the mononuclear phagocyte system is
complicated by the shared expression of cell surface markers such as CD11c. In this study …
complicated by the shared expression of cell surface markers such as CD11c. In this study …
Regulatory networks involving STATs, IRFs, and NFκB in inflammation
E Platanitis, T Decker - Frontiers in immunology, 2018 - frontiersin.org
Cells engaging in inflammation undergo drastic changes of their transcriptomes. In order to
tailor these alterations in gene expression to the requirements of the inflammatory process …
tailor these alterations in gene expression to the requirements of the inflammatory process …
Human CD141+ (BDCA-3)+ dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens
SL Jongbloed, AJ Kassianos, KJ McDonald… - Journal of Experimental …, 2010 - rupress.org
The characterization of human dendritic cell (DC) subsets is essential for the design of new
vaccines. We report the first detailed functional analysis of the human CD141+ DC subset …
vaccines. We report the first detailed functional analysis of the human CD141+ DC subset …