Here we review studies that provided important information about conformational properties
of DNA using circular dichroic (CD) spectroscopy. The conformational properties include the …

This review is focused on the structural and physicochemical aspects of metal cation
coordination to G-Quadruplexes (GQ) and their effects on GQ stability and conformation. G …

Guanine-rich DNA sequences of a particular form have the ability to fold into four-stranded
structures called G-quadruplexes. In this paper, we present a working rule to predict which …

Certain G-rich DNA sequences readily form four-stranded structures called G-quadruplexes.
These sequence motifs are located in telomeres as a repeated unit, and elsewhere in the …

Guanine-rich nucleic acid sequences can adopt noncanonical four-stranded secondary
structures called guanine (G)-quadruplexes. Bioinformatics analysis suggests that G …

Telomeres are DNA-protein complexes that cap and protect the ends of linear
chromosomes. In almost all species, telomeric DNA has a G/C strand bias, and the short …

Ciliates contain two types of nuclei: a micronucleus and a macronucleus. The micronucleus
serves as the germ line nucleus but does not express its genes. The macronucleus provides …

The G-quadruplex is an alternative DNA structural motif that is considered to be functionally
important in the mammalian genome for transcriptional regulation, DNA replication and …

To be functional, nucleic acids need to adopt particular threedimensional structures. For a
long time DNA was regarded as a rigid and passive molecule with the sole purpose to store …

Circular dichroism (CD) is remarkably sensitive to the conformational states of nucleic acids;
therefore, CD spectroscopy has been used to study most features of DNA and RNA …