The semantics of microglia activation: neuroinflammation, homeostasis, and stress

SC Woodburn, JL Bollinger, ES Wohleb - Journal of neuroinflammation, 2021 - Springer
Microglia are emerging as critical regulators of neuronal function and behavior in nearly
every area of neuroscience. Initial reports focused on classical immune functions of …

Neuroinflammatory mechanisms in ischemic stroke: focus on cardioembolic stroke, background, and therapeutic approaches

CD Maida, RL Norrito, M Daidone… - International journal of …, 2020 - mdpi.com
One of the most important causes of neurological morbidity and mortality in the world is
ischemic stroke. It can be a result of multiple events such as embolism with a cardiac origin …

[HTML][HTML] Inflammation: the common pathway of stress-related diseases

YZ Liu, YX Wang, CL Jiang - Frontiers in human neuroscience, 2017 - frontiersin.org
While modernization has dramatically increased lifespan, it has also witnessed the nature of
stress has changed dramatically. Chronic stress result failures of homeostasis and thus lead …

Neuroinflammation: the devil is in the details

DJ DiSabato, N Quan, JP Godbout - Journal of neurochemistry, 2016 - Wiley Online Library
There is significant interest in understanding inflammatory responses within the brain and
spinal cord. Inflammatory responses that are centralized within the brain and spinal cord are …

The effects of acute psychological stress on circulating and stimulated inflammatory markers: a systematic review and meta-analysis

AL Marsland, C Walsh, K Lockwood… - Brain, behavior, and …, 2017 - Elsevier
Inflammatory reactivity to acute laboratory stress is thought to reflect individual differences in
responsivity to environmental stressors and may confer future health risk. To characterize …

Brain–heart interaction: cardiac complications after stroke

Z Chen, P Venkat, D Seyfried, M Chopp, T Yan… - Circulation …, 2017 - Am Heart Assoc
Neurocardiology is an emerging specialty that addresses the interaction between the brain
and the heart, that is, the effects of cardiac injury on the brain and the effects of brain injury …

Stress and neuroinflammation: a systematic review of the effects of stress on microglia and the implications for mental illness

MA Calcia, DR Bonsall, PS Bloomfield, S Selvaraj… - …, 2016 - Springer
Rationale Psychosocial stressors are a well-documented risk factor for mental illness.
Neuroinflammation, in particular elevated microglial activity, has been proposed to mediate …

Mental health and periodontal and peri‐implant diseases

J Ball, I Darby - Periodontology 2000, 2022 - Wiley Online Library
Mental health disorders, particularly depression and anxiety, affect a significant number of
the global population. Several pathophysiological pathways for these disorders have been …

Integrating neuroimmune systems in the neurobiology of depression

ES Wohleb, T Franklin, M Iwata… - Nature Reviews …, 2016 - nature.com
Data from clinical and preclinical studies indicate that immune dysregulation, specifically of
inflammatory processes, is associated with symptoms of major depressive disorder (MDD) …

[HTML][HTML] The microbiome: a key regulator of stress and neuroinflammation

K Rea, TG Dinan, JF Cryan - Neurobiology of stress, 2016 - Elsevier
There is a growing emphasis on the relationship between the complexity and diversity of the
microorganisms that inhabit our gut (human gastrointestinal microbiota) and health/disease …