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[HTML][HTML] Sepsis—pathophysiology and therapeutic concepts
D Jarczak, S Kluge, A Nierhaus - Frontiers in medicine, 2021 - frontiersin.org
Sepsis is a life-threatening condition and a global disease burden. Today, the
heterogeneous syndrome is defined as severe organ dysfunction caused by a dysregulated …
heterogeneous syndrome is defined as severe organ dysfunction caused by a dysregulated …
Paediatric and neonatal sepsis and inflammation
Sepsis has a huge impact on global mortality and has been declared as a priority by the
World Health organisation the WHO. Children have a high incidence of sepsis especially in …
World Health organisation the WHO. Children have a high incidence of sepsis especially in …
An immune dysfunction score for stratification of patients with acute infection based on whole-blood gene expression
Dysregulated host responses to infection can lead to organ dysfunction and sepsis, causing
millions of global deaths each year. To alleviate this burden, improved prognostication and …
millions of global deaths each year. To alleviate this burden, improved prognostication and …
Development of exhausted memory monocytes and underlying mechanisms
Pathogenic inflammation and immuno-suppression are cardinal features of exhausted
monocytes increasingly recognized in septic patients and murine models of sepsis …
monocytes increasingly recognized in septic patients and murine models of sepsis …
Explainable machine-learning model for prediction of in-hospital mortality in septic patients requiring intensive care unit readmission
C Hu, L Li, Y Li, F Wang, B Hu, Z Peng - Infectious Diseases and Therapy, 2022 - Springer
Introduction Septic patients requiring intensive care unit (ICU) readmission are at high risk of
mortality, but research focusing on the association of ICU readmission due to sepsis and …
mortality, but research focusing on the association of ICU readmission due to sepsis and …
Six potential biomarkers in septic shock: a deep bioinformatics and prospective observational study
C Kong, Y Zhu, X ** pediatric sepsis
X Zhang, Y Cui, X Ding, S Liu, B Han, X Duan… - …, 2021 - Taylor & Francis
Pediatric sepsis is a great threat to death worldwide. However, the pathogenesis has not
been clearly understood until now in sepsis. This study identified differentially expressed …
been clearly understood until now in sepsis. This study identified differentially expressed …
[HTML][HTML] Neutrophil profiles of pediatric COVID-19 and multisystem inflammatory syndrome in children
Multisystem inflammatory syndrome in children (MIS-C) is a delayed-onset, COVID-19-
related hyperinflammatory illness characterized by severe acute respiratory syndrome …
related hyperinflammatory illness characterized by severe acute respiratory syndrome …
Mechanisms and modulation of sepsis-induced immune dysfunction in children
LB Mithal, M Arshad, LR Swigart, A Khanolkar… - Pediatric …, 2022 - nature.com
Immunologic responses during sepsis vary significantly among patients and evolve over the
course of illness. Sepsis has a direct impact on the immune system due to adverse alteration …
course of illness. Sepsis has a direct impact on the immune system due to adverse alteration …
A study of the recent trends of immunology: Key challenges, domains, applications, datasets, and future directions
The human immune system is very complex. Understanding it traditionally required
specialized knowledge and expertise along with years of study. However, in recent times …
specialized knowledge and expertise along with years of study. However, in recent times …