Recent progress in anticoagulant therapy: oral direct inhibitors of thrombin and factor Xa

KA Bauer - Journal of thrombosis and haemostasis, 2011 - Wiley Online Library
While parenteral anticoagulants such as unfractionated and low molecular weight heparins
and the oral vitamin K antagonists are effective for the prevention and treatment of …

The potential role of new oral anticoagulants in the prevention and treatment of thromboembolism

T Mavrakanas, H Bounameaux - Pharmacology & therapeutics, 2011 - Elsevier
Thromboembolic disorders are among the major causes of morbidity and mortality, and
anticoagulation remains the cornerstone of prevention and treatment of these disorders …

Venous thromboembolism: annualised United States models for total, hospital-acquired and preventable costs utilising long-term attack rates

CE Mahan, ME Borrego, AL Woersching… - Thrombosis and …, 2012 - thieme-connect.com
Healthcare reform is upon the United States (US) healthcare system. Prioritisation of
preventative efforts will guide necessary transitions within the US healthcare system. While …

Healthcare utilization and expenditures among patients with venous thromboembolism following gastrointestinal cancer surgery

M Khalil, S Woldesenbet, MM Munir, MMM Khan… - Journal of …, 2024 - Elsevier
Background We sought to assess healthcare utilization and expenditures among patients
who developed venous thromboembolism (VTE) after gastrointestinal cancer surgery …

Comparison of postoperative complications after total hip arthroplasty among patients receiving aspirin, enoxaparin, warfarin, and factor Xa inhibitors

P Agaba, BJ Kildow, H Dhotar, TM Seyler… - Journal of …, 2017 - Elsevier
Optimal prophylaxis for prevention of venous thromboembolism (VTE) after total joint
arthroplasty (TJA) remains debated. The purpose of this study was to compare postoperative …

Rivaroxaban: an oral factor Xa inhibitor

TF Thomas, V Ganetsky, SA Spinler - Clinical therapeutics, 2013 - Elsevier
BACKGROUND: Currently available anticoagulants utilized for venous thromboembolism
(VTE) treatment and prevention and stroke prevention in patients with atrial fibrillation (AF) …

Benefit–risk profile of non-vitamin K antagonist oral anticoagulants in the management of venous thromboembolism

J Beyer-Westendorf, W Ageno - Thrombosis and haemostasis, 2015 - thieme-connect.com
The prevention and treatment of venous thromboembolism (VTE) remains a clinical
challenge, primarily owing to drawbacks associated with the use of heparins and vitamin K …

Cost-effectiveness of apixaban for prevention of venous thromboembolic events in patients after gynecologic cancer surgery

A Glickman, A Brennecke, A Tayebnejad, K Matsuo… - Gynecologic …, 2020 - Elsevier
Objective The cost-effectiveness of apixaban was compared with enoxaparin for prevention
of postoperative venothromboembolic events (VTE) in gynecologic oncology patients …

[HTML][HTML] Direct oral anticoagulants are a potential alternative to low-molecular-weight heparin for thromboprophylaxis in trauma patients sustaining lower extremity …

CJ Nederpelt, KA Breen, MW El Hechi, P Krijnen… - Journal of Surgical …, 2021 - Elsevier
Background Trauma patients are at a significant risk of venous thromboembolism (VTE), with
lower extremity fractures (LEF) being independent risk factors. Use of direct oral …

Rivaroxaban versus enoxaparin for the prevention of venous thromboembolism after total knee arthroplasty: a meta-analysis

HF Huang, SS Li, XT Yang, Q **e, XB Tian - Medicine, 2018 - journals.lww.com
Objective: This article analyzed the clinical efficacy and tolerability of rivaroxaban and
enoxaparin in patients undergoing total knee arthroplasty (TKA) surgery. Methods: Five …