Physiological transformation with remodeling of the uteroplacental spiral arteries is key to a
successful placentation and normal placental function. It is an intricate process that involves …

Placental-related fetal growth restriction arises primarily due to deficient remodeling of the
uterine spiral arteries supplying the placenta during early pregnancy. The resultant …

The pharmacokinetics of vitamin C (vitC) is indeed complex. Regulated primarily by a family
of saturable sodium dependent vitC transporters (SVCTs), the absorption and elimination …

Placenta accreta has been described as a spectrum of abnormal attachment of villous tissue
to the uterine wall, ranging from superficial attachment to the inner myometrium without …

Preeclampsia (PE) is a multifactorial pregnancy disease, characterized by new-onset
gestational hypertension with (or without) proteinuria or end-organ failure, exclusively …

Interventions to prevent pregnancy complications have been largely unsuccessful. We
suggest this is because the foundation for a healthy pregnancy is laid prior to the …

Oxidative stress is caused by an imbalance between the production of reactive oxygen
species (ROS) in cells and tissues and the ability of a biological system to detoxify them …

The role of oxidative stress in the physiopathology of human pregnancy is of particular
interest. Pregnancy is well-known to increase the oxidative stress, mainly produced by a …

The placenta is arguably the most important organ of the body, but paradoxically the most
poorly understood. During its transient existence, it performs actions that are later taken on …

Preeclampsia (PE) affects 5‐8% of pregnant women, and it is the major cause of perinatal
morbidity and mortality. It is defined as arterial hypertension in women after 20 weeks of …