Highlights•Liquid-liquid phase separation underlies the formation of membraneless
organelles within cells.•Theory and molecular simulations help to relate interactions at the …

The aversion of hydrophobic solutes for water drives diverse interactions and assemblies
across materials science, biology, and beyond. Here, we review the theoretical …

The functional structure of proteins results from marginally stable folded conformations.
Reversible unfolding, irreversible denaturation, and deterioration can be caused by …

Protein structural biology came a long way since the determination of the first three-
dimensional structure of myoglobin about six decades ago. Across this period, X-ray …

Naturally occurring metamorphic proteins have the ability to interconvert from one folded
state to another through either a limited set of mutations or by way of a change in the local …

Rare events are processes that occur upon the emergence of unlikely fluctuations. Unlike
what their name suggests, rare events are fairly ubiquitous in nature, as the occurrence of …

The adverse physiological conditions have been long known to impact protein synthesis,
folding and functionality. Major physiological factors such as the effect of pH, temperature …

In this perspective article we highlight research opportunities and challenges in probing
structural dynamics of molecular systems using X-ray Photon Correlation Spectroscopy …

Although it is well understood that the graph of the free energy of unfolding (ΔG) of a
globular protein with temperature approximates to a negative parabola, there is as yet no …

The quality of dried fish products differs based on the drying method employed owing to the
different drying principles, with changes in protein affecting the quality of these products …