Mechanochemical feedback loops in development and disease

E Hannezo, CP Heisenberg - Cell, 2019 - cell.com
There is increasing evidence that both mechanical and biochemical signals play important
roles in development and disease. The development of complex organisms, in particular …

Making and sha** endochondral and intramembranous bones

GL Galea, MR Zein, S Allen… - Developmental …, 2021 - Wiley Online Library
Skeletal elements have a diverse range of shapes and sizes specialized to their various
roles including protecting internal organs, locomotion, feeding, hearing, and vocalization …

Polyamide membranes with nanoscale Turing structures for water purification

Z Tan, S Chen, X Peng, L Zhang, C Gao - Science, 2018 - science.org
The emergence of Turing structures is of fundamental importance, and designing these
structures and develo** their applications have practical effects in chemistry and biology …

[HTML][HTML] Positional information and reaction-diffusion: two big ideas in developmental biology combine

J Green, J Sharpe - Development, 2015 - journals.biologists.com
One of the most fundamental questions in biology is that of biological pattern: how do the
structures and shapes of organisms arise? Undoubtedly, the two most influential ideas in …

Mechanochemical principles of spatial and temporal patterns in cells and tissues

A Bailles, EW Gehrels, T Lecuit - Annual review of cell and …, 2022 - annualreviews.org
Patterns are ubiquitous in living systems and underlie the dynamic organization of cells,
tissues, and embryos. Mathematical frameworks have been devised to account for the self …

On having no head: cognition throughout biological systems

F Baluška, M Levin - Frontiers in psychology, 2016 - frontiersin.org
The central nervous system (CNS) underlies memory, perception, decision-making, and
behavior in numerous organisms. However, neural networks have no monopoly on the …

Diffusiophoresis-enhanced Turing patterns

BM Alessio, A Gupta - Science Advances, 2023 - science.org
Turing patterns are fundamental in biophysics, emerging from short-range activation and
long-range inhibition processes. However, their paradigm is based on diffusive transport …

Self-organization of stem cells into embryos: a window on early mammalian development

MN Shahbazi, ED Siggia, M Zernicka-Goetz - Science, 2019 - science.org
Embryonic development is orchestrated by robust and complex regulatory mechanisms
acting at different scales of organization. In vivo studies are particularly challenging for …

Morphogenesis in robot swarms

I Slavkov, D Carrillo-Zapata, N Carranza, X Diego… - Science Robotics, 2018 - science.org
Morphogenesis allows millions of cells to self-organize into intricate structures with a wide
variety of functional shapes during embryonic development. This process emerges from …

Reconstitution of morphogen shuttling circuits

R Zhu, LA Santat, JS Markson, N Nandagopal… - Science …, 2023 - science.org
Develo** tissues form spatial patterns by establishing concentration gradients of diffusible
signaling proteins called morphogens. The bone morphogenetic protein (BMP) morphogen …