Interleukin-17 in chronic inflammatory neurological diseases

J Milovanovic, A Arsenijevic, B Stojanovic… - Frontiers in …, 2020 - frontiersin.org
A critical role for IL-17, a cytokine produced by T helper 17 (Th17) cells, has been indicated
in the pathogenesis of chronic inflammatory and autoimmune diseases. A positive effect of …

Where do we stand after decades of studying human cytomegalovirus?

F Gugliesi, A Coscia, G Griffante, G Galitska… - Microorganisms, 2020 - mdpi.com
Human cytomegalovirus (HCMV), a linear double-stranded DNA betaherpesvirus belonging
to the family of Herpesviridae, is characterized by widespread seroprevalence, ranging …

Subversion of cellular autophagosomal machinery by RNA viruses

WT Jackson, TH Giddings Jr, MP Taylor… - PLoS …, 2005 - journals.plos.org
Infection of human cells with poliovirus induces the proliferation of double-membraned
cytoplasmic vesicles whose surfaces are used as the sites of viral RNA replication and …

[HTML][HTML] Virus inhibition of RIP3-dependent necrosis

JW Upton, WJ Kaiser, ES Mocarski - Cell host & microbe, 2010 - cell.com
Viral infection activates cytokine expression and triggers cell death, the modulation of which
is important for successful pathogenesis. Necroptosis is a form of programmed necrosis …

Human cytomegalovirus UL131-128 genes are indispensable for virus growth in endothelial cells and virus transfer to leukocytes

G Hahn, MG Revello, M Patrone, E Percivalle… - Journal of …, 2004 - Am Soc Microbiol
Human cytomegalovirus (HCMV), a ubiquitous human pathogen, is the leading cause of
birth defects and morbidity in immunocompromised patients and a potential trigger for …

Immunomodulation by cytomegaloviruses: manipulative strategies beyond evasion

ES Mocarski - Trends in microbiology, 2002 - cell.com
Human cytomegalovirus (CMV) remains the major infectious cause of birth defects as well
as an important opportunistic pathogen. Individuals infected with CMV mount a strong …

Mouse model of cytomegalovirus disease and immunotherapy in the immunocompromised host: Predictions for medical translation that survived the “test of time”

MJ Reddehase, NAW Lemmermann - Viruses, 2018 - mdpi.com
Human Cytomegalovirus (hCMV), which is the prototype member of the β-subfamily of the
herpesvirus family, is a pathogen of high clinical relevance in recipients of hematopoietic …

Virus progeny of murine cytomegalovirus bacterial artificial chromosome pSM3fr show reduced growth in salivary Glands due to a fixed mutation of MCK-2

S Jordan, J Krause, A Prager, M Mitrovic… - Journal of …, 2011 - Am Soc Microbiol
Murine cytomegalovirus (MCMV) Smith strain has been cloned as a bacterial artificial
chromosome (BAC) named pSM3fr and used for analysis of virus gene functions in vitro and …

Viral evasion of natural killer cells

JS Orange, MS Fassett, LA Koopman, JE Boyson… - Nature …, 2002 - nature.com
Viruses have evolved mechanisms to avoid the host immune system, including means of
esca** detection by both the innate and adaptive immune responses. Natural killer (NK) …

There is always another way! cytomegalovirus' multifaceted dissemination schemes

JW Jackson, T Sparer - Viruses, 2018 - mdpi.com
Human cytomegalovirus (HCMV) is a β-herpes virus that is a significant pathogen within
immune compromised populations. HCMV morbidity is induced through viral dissemination …