Peptide and protein nanoparticle conjugates: versatile platforms for biomedical applications

CD Spicer, C Jumeaux, B Gupta… - Chemical society …, 2018 - pubs.rsc.org
Peptide–and protein–nanoparticle conjugates have emerged as powerful tools for
biomedical applications, enabling the treatment, diagnosis, and prevention of disease. In …

Cell penetrating peptides: classification, mechanisms, methods of study, and applications

A Gori, G Lodigiani, SG Colombarolli… - …, 2023 - Wiley Online Library
Cell‐penetrating peptides (CPPs) encompass a class of peptides that possess the
remarkable ability to cross cell membranes and deliver various types of cargoes, including …

Self assembling nanoparticle enzyme clusters provide access to substrate channeling in multienzymatic cascades

JC Breger, JN Vranish, E Oh, MH Stewart… - Nature …, 2023 - nature.com
Access to efficient enzymatic channeling is desired for improving all manner of designer
biocatalysis. We demonstrate that enzymes constituting a multistep cascade can self …

Detecting biothreat agents: From current diagnostics to develo** sensor technologies

SA Walper, G Lasarte Aragonés, KE Sapsford… - ACS …, 2018 - ACS Publications
Although a fundamental understanding of the pathogenicity of most biothreat agents has
been elucidated and available treatments have increased substantially over the past …

Cell-penetrating peptide: a means of breaking through the physiological barriers of different tissues and organs

J Xu, AR Khan, M Fu, R Wang, J Ji, G Zhai - Journal of Controlled Release, 2019 - Elsevier
The selective infiltration of cell membranes and tissue barriers often blocks the entry of most
active molecules. This natural defense mechanism prevents the invasion of exogenous …

[HTML][HTML] Peptide-nanoparticle conjugates as a theranostic platform

S Kim, YH No, R Sluyter, K Konstantinov… - Coordination Chemistry …, 2024 - Elsevier
Theranostic platforms have emerged as advanced systems integrating diagnostic and
therapeutic agents to enable personalized medicine tailored to the specific characteristics of …

[HTML][HTML] Oxytocin and vasopressin signaling in health and disease

M Perisic, K Woolcock, A Hering, H Mendel… - Trends in Biochemical …, 2024 - cell.com
Neurohypophysial peptides are ancient and evolutionarily highly conserved neuropeptides
that regulate many crucial physiological functions in vertebrates and invertebrates. The …

Designer peptide and protein dendrimers: a cross-sectional analysis

R Sapra, RP Verma, GP Maurya, S Dhawan… - Chemical …, 2019 - ACS Publications
Dendrimers have attracted immense interest in science and technology due to their unique
chemical structure that offers a myriad of opportunities for researchers. Dendritic design …

Enzyme-Responsive Modular Peptides Enhance Tumor Penetration of Quantum Dots via Charge Reversal Strategy

Q Dai, Z Du, L **g, R Zhang… - ACS Applied Materials & …, 2024 - ACS Publications
Quantum dots (QDs) are colloidal semiconductor nanoparticles acting as fluorescent probes
for detection, disease diagnosis, and photothermal and photodynamic therapy. However …

Enhancing coupled enzymatic activity by colocalization on nanoparticle surfaces: Kinetic evidence for directed channeling of intermediates

JN Vranish, MG Ancona, E Oh, K Susumu… - ACS …, 2018 - ACS Publications
Multistep enzymatic cascades are becoming more prevalent in industrial settings as
engineers strive to synthesize complex products and pharmaceuticals in economical …