Over the past decade, a series of experimental strategies for mass spectrometry based
quantitative proteomics and corresponding computational methodology for the processing of …

Modern analytical technologies afford comprehensive and quantitative investigation of a
multitude of different metabolites. Typical metabolomic experiments can therefore produce …

Ticks transmit more pathogens to humans and animals than any other arthropod. We
describe the 2.1 Gbp nuclear genome of the tick, Ixodes scapularis (Say), which vectors …

Background Detection of low abundance metabolites is important for de novo map** of
metabolic pathways related to diet, microbiome or environmental exposures. Multiple …

Unlike plasma and most biological fluids which have solute concentrations that are tightly
controlled, urine volume can vary widely based upon water consumption and other …

Ultra-performance liquid chromatography coupled to mass spectrometry (UPLC/MS) has
been used increasingly for measuring changes of low molecular weight metabolites in …

Abstract Two LC‐ESI‐MS methods for the analysis of antibody glycosylation are presented.
In the first approach, tryptic glycopeptides are separated by RP chromatography and …

Metabolomics encompasses the study of small molecules in a biological sample. Liquid
Chromatography coupled with Mass Spectrometry (LC–MS) profiling is an important …

Liquid chromatography-mass spectrometry is widely used for comparative replicate sample
analysis in proteomics, lipidomics and metabolomics. Before statistical comparison …

Background Liquid chromatography coupled to mass spectrometry (LC-MS) has become a
prominent tool for the analysis of complex proteomics and metabolomics samples. In many …