Mechanistic insight is achieved only when experiments are employed to test formal or
computational models. Furthermore, in analogy to lesion studies, phantom perception may …

Tinnitus is a phantom auditory sensation in the absence of external sounds, while
hyperacusis is an atypical sensitivity to external sounds that leads them to be perceived as …

OTOF mutations are the principal causes of auditory neuropathy. There are reports on Otof‐
related gene therapy in mice, but there is no preclinical research on the drug evaluations …

Many aging adults experience some form of hearing problems that may arise from auditory
peripheral damage. However, it has been increasingly acknowledged that hearing loss is …

The global impact of hearing loss and related auditory dysfunction including tinnitus and
hyperacusis on human health is significant and growing. A substantial body of literature has …

The hippocampus and parahippocampal gyrus have been implicated as part of a tinnitus
network by a number of studies. These structures are usually considered in the context of a …

Age-related hearing loss (ARHL) is the most prevalent sensory deficit in the elderly and
constitutes the third highest risk factor for dementia. Lifetime noise exposure, genetic …

Importance: Chronic subjective tinnitus, the perception of sound without an external source
for longer than six months, may be a greatly debilitating condition for some people, and is …

Neuronal hyperexcitability in the central auditory pathway linked to reduced inhibitory
activity is associated with numerous forms of hearing loss, including noise damage, age …

Tinnitus is the perception of a ringing, buzzing or hissing sound “in the ear” without external
stimulation. Previous research has demonstrated changes in resting-state functional …