Myocardial infarction is a prevalent major cardiovascular event that arises from myocardial
ischemia with or without reperfusion, and basic and translational research is needed to …

Protein phosphatases act as key regulators of multiple important cellular processes and are
attractive therapeutic targets for various diseases. Although extensive effort has been …

Research into cardiac autonomic control has received great interest in the past 20 years,
and we are now at a critical juncture with regard to the clinical translation of the experimental …

Dysfunction of the autonomic nervous system has been implicated in the pathogenesis of
cardiovascular disease, including congestive heart failure and cardiac arrhythmias. Despite …

Cardiac arrhythmias are a major cause of morbidity and mortality worldwide. Although
recent advances in cell-based models, including human-induced pluripotent stem cell …

Protein tyrosine phosphatases (PTPs) are a family of enzymes essential for numerous
cellular processes, and several PTPs have been validated as therapeutic targets for human …

Neuronal elements distributed throughout the cardiac nervous system, from the level of the
insular cortex to the intrinsic cardiac nervous system, are in constant communication with …

Ischemic heart disease is the most common cause of lethal ventricular arrhythmias and
sudden cardiac death (SCD). In patients who are at high risk after myocardial infarction …

There is a lack of understanding in the cardiac remodeling field regarding the use of
nonreperfused myocardial infarction (MI) and reperfused MI in animal models of MI. This …

Sympathetic activity plays an important role in modulation of cardiac rhythm. Indeed, while
exerting positive tropic effects in response to physiologic and pathologic stressors, β …