Exosomes are extracellular vesicles that in recent years have received special attention for
their regulatory functions in numerous biological processes. Recent evidence suggests a …

It is now becoming well established that vesicles are released from a broad range of cell
types and are involved in cell-to-cell communication, both in physiological and pathological …

Extracellular vesicles (EVs), such as exosomes, can mediate long-distance communication
between cells by delivering biomolecular cargo. It is speculated that EVs undergo back …

Exosome-based drug delivery is emerging as a promising field with the potential to
revolutionize therapeutic interventions. Exosomes, which are small extracellular vesicles …

Non-coding RNAs represent a significant proportion of the human genome. After having
been considered as 'junk'for a long time, non-coding RNAs are now well established as …

Exosomes are small (∼ 30–140 nm) lipid bilayer-enclosed particles of endosomal origin.
They are a subset of extracellular vesicles (EVs) that are secreted by most cell types. There …

Endothelial cell (EC) CD36 controls tissue fatty acid (FA) uptake. Here we examine how ECs
transfer FAs. FA interaction with apical membrane CD36 induces Src phosphorylation of …

Cancer-associated fibroblasts (CAFs) comprise the majority of the tumor bulk of pancreatic
ductal adenocarcinomas (PDACs). Current efforts to eradicate these tumors focus …

We have uncovered the existence of extracellular vesicle (EV)-mediated signaling between
cell types within the adipose tissue (AT) proper. This phenomenon became evident in our …

Neurons require mechanisms to maintain ATP homeostasis in axons, which are highly
vulnerable to bioenergetic failure. Here, we elucidate a transcellular signaling mechanism …