Fluorescent nanoparticles for super-resolution imaging

W Li, GS Kaminski Schierle, B Lei, Y Liu… - Chemical …, 2022 - ACS Publications
Super-resolution imaging techniques that overcome the diffraction limit of light have gained
wide popularity for visualizing cellular structures with nanometric resolution. Following the …

Xanthene, cyanine, oxazine and BODIPY: the four pillars of the fluorophore empire for super-resolution bioimaging

S Samanta, K Lai, F Wu, Y Liu, S Cai, X Yang… - Chemical Society …, 2023 - pubs.rsc.org
In the realm of biological research, the invention of super-resolution microscopy (SRM) has
enabled the visualization of ultrafine sub-cellular structures and their functions in live cells at …

Hybrid small-molecule/protein fluorescent probes

M Minoshima, SI Reja, R Hashimoto, K Iijima… - Chemical …, 2024 - ACS Publications
Hybrid small-molecule/protein fluorescent probes are powerful tools for visualizing protein
localization and function in living cells. These hybrid probes are constructed by diverse site …

Biomedical applications of copper-free click chemistry: in vitro, in vivo, and ex vivo

E Kim, H Koo - Chemical science, 2019 - pubs.rsc.org
Recently, click chemistry has provided important advances in biomedical research fields.
Particularly, copper-free click chemistry including strain-promoted azide–alkyne …

Advanced imaging and labelling methods to decipher brain cell organization and function

D Choquet, M Sainlos, JB Sibarita - Nature Reviews Neuroscience, 2021 - nature.com
The brain is arguably the most complex organ. The branched and extended morphology of
nerve cells, their subcellular complexity, the multiplicity of brain cell types as well as their …

Smart photochromic materials triggered with visible light

AL Leistner, ZL Pianowski - European Journal of Organic …, 2022 - Wiley Online Library
Molecular photoswitches reversibly convert the energy of light into a variety of structural
changes at the molecular level. They can be integrated into smart materials with broad …

Bioorthogonally activatable cyanine dye with torsion-induced disaggregation for in vivo tumor imaging

X Zhang, J Gao, Y Tang, J Yu, SS Liew, C Qiao… - Nature …, 2022 - nature.com
Advancement of bioorthogonal chemistry in molecular optical imaging lies in expanding the
repertoire of fluorophores that can undergo fluorescence signal changes upon …

Near-infrared fluorescent probes: a next-generation tool for protein-labeling applications

SI Reja, M Minoshima, Y Hori, K Kikuchi - Chemical Science, 2021 - pubs.rsc.org
The development of near-infrared (NIR) fluorescent probes over the past few decades has
changed the way that biomolecules are imaged, and thus represents one of the most rapidly …

Defining the basis of cyanine phototruncation enables a new approach to single-molecule localization microscopy

SS Matikonda, DA Helmerich, M Meub… - ACS Central …, 2021 - ACS Publications
The light-promoted conversion of extensively used cyanine dyes to blue-shifted emissive
products has been observed in various contexts. However, both the underlying mechanism …

Photoactivatable fluorescent dyes with hydrophilic caging groups and their use in multicolor nanoscopy

AN Butkevich, M Weber… - Journal of the …, 2021 - ACS Publications
We propose a series of fluorescent dyes with hydrophilic carbamate caging groups that
undergo rapid photoactivation under UV (≤ 400 nm) irradiation but do not undergo spurious …