Priorities in Cardio-Oncology Basic and Translational Science: GCOS 2023 Symposium Proceedings: JACC: CardioOncology State-of-the-Art Review

FN Salloum, CG Tocchetti, P Ameri, H Ardehali… - Cardio Oncology, 2023 - jacc.org
Despite improvements in cancer survival, cancer therapy–related cardiovascular toxicity has
risen to become a prominent clinical challenge. This has led to the growth of the burgeoning …

Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination or SARS-CoV-2 infection

M Patone, XW Mei, L Handunnetthi, S Dixon… - Nature medicine, 2022 - nature.com
Although myocarditis and pericarditis were not observed as adverse events in coronavirus
disease 2019 (COVID-19) vaccine trials, there have been numerous reports of suspected …

Biomarker trends, incidence, and outcomes of immune checkpoint inhibitor–induced myocarditis

A Vasbinder, YA Chen, A Procureur, A Gradone… - Cardio Oncology, 2022 - jacc.org
Background Myocarditis is a dreaded and unpredictable complication of immune checkpoint
inhibitors (ICI). We sought to determine whether routinely measured biomarkers could be …

Risk factors for immune checkpoint inhibitor–mediated cardiovascular toxicities

LI Yousif, EM Screever, D Versluis… - Current Oncology …, 2023 - Springer
Abstract Purpose of Review Immune checkpoint inhibitors (ICIs) have improved the field of
cancer, especially in patients with advanced malignancies. Nevertheless, cardiovascular …

[HTML][HTML] Pathophysiology of immune checkpoint inhibitor-induced myocarditis

R Jiménez-Alejandre, I Ruiz-Fernandez, P Martin - Cancers, 2022 - mdpi.com
Simple Summary Myocarditis is an infrequent but highly hazardous complication of the
cancer therapy of immune checkpoint inhibitors (ICIs). The study of the pathophysiology of …

Murine MHC-deficient nonobese diabetic mice carrying human HLA-DQ8 develop severe myocarditis and myositis in response to anti–PD-1 immune checkpoint …

JJ Racine, JF Bachman, JG Zhang… - The Journal of …, 2024 - journals.aai.org
Myocarditis has emerged as an immune-related adverse event of immune checkpoint
inhibitor (ICI) cancer therapy associated with significant mortality. To ensure patients …

Optimal timing of steroid initiation in response to CTLA-4 antibody in metastatic cancer: A mathematical model

N Siewe, A Friedman - Plos one, 2022 - journals.plos.org
Immune checkpoint inhibitors, introduced in recent years, have revolutionized the treatment
of many cancers. However, the toxicity associated with this therapy may cause severe …

Immunotherapy: A new target for cancer cure

F Zhao, D Shen, M Shang, H Yu, X Zuo… - Oncology …, 2023 - spandidos-publications.com
Cancer is the leading cause of death globally and there is a worldwide cancer epidemic.
Immunotherapy has emerged as a promising anticancer therapy. In particular, oncolytic …