The use of antifungal drugs in the therapy of fungal diseases can lead to the development of
antifungal resistance. Resistance has been described for virtually all antifungal agents in …

Antifungal therapy is a central component of patient management for acute and chronic
mycoses. Yet, treatment choices are restricted because of the sparse number of antifungal …

Aspergillus fumigatus remains the most common species in all pulmonary syndromes,
followed by Aspergillus flavus which is a common cause of allergic rhinosinusitis …

Fungal biofilm infections have become increasingly recognised as a significant clinical
problem. One of the major reasons behind this is the impact that these have upon treatment …

Aspergillus fumigatus is the main causal agent of invasive aspergillosis (IA), however other
species of the genus can also cause IA, such as Aspergillus flavus, Aspergillus terreus …

Aspergillus fumigatus is an opportunistic pathogen that causes 90% of invasive aspergillosis
(IA) due to Aspergillus genus, with a 50–95% mortality rate. It has been postulated that …

Objectives Recent increases in triazole resistance in Aspergillus fumigatus have been
attributed primarily to target site (cyp51A) mutations. A recent survey of resistant isolates in …

The significant increase in the use of antifungal agents, both for the treatment of candidiasis
and invasive aspergillosis and as azole fungicides in agricultural crop protection has …

Secondary metabolites, including toxins and melanins, have been implicated as virulence
attributes in invasive aspergillosis. Although not definitively proved, this supposition is …

Invasive aspergillosis is a life-threatening mycosis caused by the pathogenic fungus
Aspergillus. The predominant causal species is Aspergillus fumigatus, and azole drugs are …