In the past decade, the asymmetric synthesis of chiral nonracemic isoquinoline alkaloids, a
family of natural products showing a wide range of structural diversity and biological and …

Dearomatization strategies in a multicomponent fashion often result in complex heterocyclic
frameworks, which have attracted the attention of chemists due to their natural product-like …

Amongst nitrogen heterocycles of different ring sizes and oxidation statuses,
dihydropyridines (DHP) occupy a prominent role due to their synthetic versatility and …

The first catalytic asymmetric cross-dehydrogenative coupling of cyclic carbamates and
terminal alkynes has been established. The reaction features high enantiocontrol and …

An unprecedented base-promoted multi-component one-pot dearomatization of N-alkyl
activated azaarenes was developed, which enabled the synthesis of complex and diverse …

N, O-aminals, molecules bearing a geminally N, O-substituted (stereogenic) carbon center,
have been recently recognized as an important class of building blocks in organic synthesis …

Given the important agricultural and medicinal application of optically pure heterocycles
bearing a trifluoromethyl group at the stereogenic carbon center in the heterocyclic …

A chiral‐NHC‐catalyzed highly diastereo‐and enantioselective dearomatizing double
Mannich reaction of isoquinolines was developed that provides a powerful and …

The catalytic enantioselective dearomatization of pyridines with nucleophiles represents a
direct and convenient access to highly valuable dihydropyridines. Available methods, mostly …

An enantioselective dearomatization of isoquinolines has been developed using chiral
anion-binding catalysis. This transformation, catalyzed by a simple and easy to prepare tert …