Bipolar disorder is a recurrent disorder that affects more than 1% of the world population and
usually has its onset during youth. Its chronic course is associated with high rates of …

The most common mood disorders are major depressive disorders and bipolar disorders
(BD). The pathophysiology of BD is complex, multifactorial, and not fully understood …

Preventive approaches have latterly gained traction for improving mental health in young
people. In this paper, we first appraise the conceptual foundations of preventive psychiatry …

The Canadian Network for Mood and Anxiety Treatments (CANMAT) previously published
treatment guidelines for bipolar disorder in 2005, along with international commentaries and …

Background The neurotrophic hypothesis postulates that mood disorders such as bipolar
disorder (BD) are associated with a lower expression of brain-derived neurotrophic factor …

Objectives In the coming generation, older adults with bipolar disorder (BD) will increase in
absolute numbers as well as proportion of the general population. This is the first report of …

Objective: To evaluate the length of the interval between the onset and the initial
management of bipolar disorder (BD). Method: We conducted a meta-analysis using the …

Broad neuropsychological deficits have been consistently demonstrated in well-established
bipolar disorder. The aim of the current study was to systematically review …

Bipolar disorder (BD) is a chronic mental illness characterized by changes in mood that
alternate between mania and hypomania or between depression and mixed states, often …

Introduction Bipolar disorder is an often disabling mental illness with a lifetime prevalence of
1%–2%, a high risk of recurrence of manic and depressive episodes, a lifelong elevated risk …