Moving from control to elimination of schistosomiasis in sub-Saharan Africa: time to change and adapt strategies
Schistosomiasis is a water borne parasitic disease of global importance and with ongoing
control the disease endemic landscape is changing. In sub-Saharan Africa, for example, the …
control the disease endemic landscape is changing. In sub-Saharan Africa, for example, the …
The road to elimination: current state of schistosomiasis research and progress towards the end game
P Ogongo, RK Nyakundi, GK Chege… - Frontiers in …, 2022 - frontiersin.org
The new WHO Roadmap for Neglected Tropical Diseases targets the global elimination of
schistosomiasis as a public health problem. To date, control strategies have focused on …
schistosomiasis as a public health problem. To date, control strategies have focused on …
Cognitive deficits and educational loss in children with schistosome infection—a systematic review and meta-analysis
Background By means of meta-analysis of information from all relevant epidemiologic
studies, we examined the hypothesis that Schistosoma infection in school-aged children …
studies, we examined the hypothesis that Schistosoma infection in school-aged children …
[HTML][HTML] Circulating Anodic Antigen (CAA): a highly sensitive diagnostic biomarker to detect active Schistosoma infections—improvement and use during SCORE
PLAM Corstjens, CJ de Dood, S Knopp… - The American journal …, 2020 - ncbi.nlm.nih.gov
The Schistosomiasis Consortium for Operational Research and Evaluation (SCORE) was
funded in 2008 to conduct research that would support country schistosomiasis control …
funded in 2008 to conduct research that would support country schistosomiasis control …
[HTML][HTML] A new global strategy for the elimination of schistosomiasis
AGP Ross, TN Chau, MT Inobaya, RM Olveda… - International Journal of …, 2017 - Elsevier
Mass drug administration utilising a single oral dose of 40 mg/kg of praziquantel (PZQ) has
been endorsed and advocated by the World Health Organisation (WHO) for the global …
been endorsed and advocated by the World Health Organisation (WHO) for the global …
Efficacy and safety of praziquantel in preschool-aged and school-aged children infected with Schistosoma mansoni: a randomised controlled, parallel-group, dose …
JT Coulibaly, G Panic, KD Silué, J Kovač… - The Lancet Global …, 2017 - thelancet.com
Background Praziquantel has been the drug of choice for schistosomiasis control for more
than 40 years, yet surprisingly, the optimal dose for children younger than 4 years is not …
than 40 years, yet surprisingly, the optimal dose for children younger than 4 years is not …
Drug metabolism and pharmacokinetics of praziquantel: A review of variable drug exposure during schistosomiasis treatment in human hosts and experimental …
G Zdesenko, F Mutapi - PLoS neglected tropical diseases, 2020 - journals.plos.org
Schistosomiasis control is heavily reliant on the drug praziquantel (PZQ), which is used as
preventive chemotherapy as part of national helminth control strategies. Given the heavy …
preventive chemotherapy as part of national helminth control strategies. Given the heavy …
A review of the genetic determinants of praziquantel resistance in Schistosoma mansoni: Is praziquantel and intestinal schistosomiasis a perfect match?
S Summers, T Bhattacharyya, F Allan… - Frontiers in Tropical …, 2022 - frontiersin.org
Schistosomiasis is a neglected tropical disease (NTD) caused by parasitic trematodes
belonging to the Schistosoma genus. The mainstay of schistosomiasis control is the delivery …
belonging to the Schistosoma genus. The mainstay of schistosomiasis control is the delivery …
Efficacy and safety of praziquantel and dihydroartemisinin piperaquine combination for treatment and control of intestinal schistosomiasis: A randomized, non …
Background Despite the reported success in reducing morbidity, praziquantel alone is
insufficient for the control and elimination of schistosomiasis, partly due to its poor efficacy …
insufficient for the control and elimination of schistosomiasis, partly due to its poor efficacy …
Schistosomiasis in the first 1000 days
Infections during the first 1000 days—the period from conception to a child's second birthday—
can have lifelong effects on health, because this is a crucial phase of growth and …
can have lifelong effects on health, because this is a crucial phase of growth and …