Biomarkers in whichever modality are tremendously important in diagnosing of disease,
tracking disease progression and clinical trials. This applies in particular for disorders with a …

Functional and structural connectivity measures, as assessed by means of functional and
diffusion MRI, are emerging as potential intermediate biomarkers for Alzheimer disease (AD) …

Introduction: Tourette syndrome (TS) is a neuropsychiatric disorder with the core
phenomenon of tics, whose origin and temporal pattern are unclear. We investigated the …

Resting‐state functional magnetic resonance imaging (rs‐fMRI) has the potential to shed
light on the pathophysiological mechanisms of Huntington's disease (HD), paving the way to …

The clinical benefits of targeting the ventral intermediate nucleus (VIM) for the treatment of
tremors in essential tremor (ET) patients suggest that the VIM is a key hub in the network of …

Tourette Syndrome (TS) is a neuropsychiatric disorder characterized by the presence of
motor and vocal tics. Major pathophysiological theories posit a dysfunction of the cortico …

Trans‐neuronal propagation of mutant huntingtin protein contributes to the organised
spread of cortico‐striatal degeneration and disconnection in Huntington's disease (HD). We …

Huntington's disease is an autosomal, dominantly inherited neurodegenerative disease
caused by an expansion of the CAG repeats in exon 1 of the huntingtin gene. Neuronal …

Huntington's disease (HD) is a progressive and fatal neurodegenerative disorder caused by
an expanded trinucleotide CAG sequence in huntingtin gene (HTT) on chromosome 4. HD …

Background Hyperkinetic movement disorders (HMD) manifest as abnormal and
uncontrollable movements. Despite reported involvement of several neural circuits, exact …