Psychedelics in psychiatry: neuroplastic, immunomodulatory, and neurotransmitter mechanisms

A Inserra, D De Gregorio, G Gobbi, M Nader - Pharmacological Reviews, 2021 - Elsevier
Mounting evidence suggests safety and efficacy of psychedelic compounds as potential
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …

Untangling the cortico-thalamo-cortical loop: cellular pieces of a knotty circuit puzzle

GMG Shepherd, N Yamawaki - Nature Reviews Neuroscience, 2021 - nature.com
Functions of the neocortex depend on its bidirectional communication with the thalamus, via
cortico-thalamo-cortical (CTC) loops. Recent work dissecting the synaptic connectivity in …

[HTML][HTML] Reconstruction of 1,000 projection neurons reveals new cell types and organization of long-range connectivity in the mouse brain

J Winnubst, E Bas, TA Ferreira, Z Wu, MN Economo… - Cell, 2019 - cell.com
Neuronal cell types are the nodes of neural circuits that determine the flow of information
within the brain. Neuronal morphology, especially the shape of the axonal arbor, provides …

Integrative and network-specific connectivity of the basal ganglia and thalamus defined in individuals

DJ Greene, S Marek, EM Gordon, JS Siegel, C Gratton… - Neuron, 2020 - cell.com
The basal ganglia, thalamus, and cerebral cortex form an interconnected network implicated
in many neurological and psychiatric illnesses. A better understanding of cortico-subcortical …

Cell-type-specific control of brainstem locomotor circuits by basal ganglia

TK Roseberry, AM Lee, AL Lalive, L Wilbrecht, A Bonci… - Cell, 2016 - cell.com
The basal ganglia (BG) are critical for adaptive motor control, but the circuit principles
underlying their pathway-specific modulation of target regions are not well understood …

The anatomy of inference: generative models and brain structure

T Parr, KJ Friston - Frontiers in computational neuroscience, 2018 - frontiersin.org
To infer the causes of its sensations, the brain must call on a generative (predictive) model.
This necessitates passing local messages between populations of neurons to update beliefs …

Striatal circuits as a common node for autism pathophysiology

MV Fuccillo - Frontiers in neuroscience, 2016 - frontiersin.org
Autism spectrum disorders (ASD) are characterized by two seemingly unrelated symptom
domains—deficits in social interactions and restrictive, repetitive patterns of behavioral …

[HTML][HTML] Brain structure and phenotypic profile of superagers compared with age-matched older adults: a longitudinal analysis from the Vallecas Project

M Garo-Pascual, C Gaser, L Zhang, J Tohka… - The Lancet Healthy …, 2023 - thelancet.com
Background Cognitive abilities, particularly memory, normally decline with age. However,
some individuals, often designated as superagers, can reach late life with the memory …

Cortico-basal ganglia plasticity in motor learning

RH Roth, JB Ding - Neuron, 2024 - cell.com
One key function of the brain is to control our body's movements, allowing us to interact with
the world around us. Yet, many motor behaviors are not innate but require learning through …

[PDF][PDF] Dehydration impairs cognitive performance: a meta-analysis

MT Wittbrodt, M Millard-Stafford - Med Sci Sports Exerc, 2018 - researchgate.net
Dehydration (DEH) is believed to impair cognitive performance but which domains are
affected and at what magnitude of body mass loss (BML) remains unclear. PURPOSE: To …