Individuals with Down syndrome (DS) commonly possess unique neurocognitive and
neurobehavioral profiles that emerge within specific developmental periods. These profiles …

The FMR1 mutations can cause a variety of disabilities, including cognitive deficits, attention-
deficit/hyperactivity disorder, autism, and other socioemotional problems, in individuals with …

Executive functions are a set of high cognitive abilities that control and regulate other
functions and behaviors and are crucial for successful adaptation. Deficits in executive …

Loss of the RNA binding protein FMRP causes Fragile X Syndrome (FXS), the most common
cause of inherited intellectual disability, yet it is unknown how FMRP function varies across …

Data on the relationships between cognitive and physical phenotypes, and a deficit of fragile
X mental retardation 1 (FMR1) gene‐specific protein product, FMRP, are presented and …

The Fragile X Syndrome (FXS) is one of the most common forms of inherited intellectual
disability in all human societies. Caused by the transcriptional silencing of a single gene, the …

Animal studies elucidating the neurobiology of fragile X syndrome (FXS) have led to multiple
controlled trials in humans, with the Aberrant Behavior Checklist-Community (ABC-C) …

Visual selective attention is the ability to attend to relevant visual information and ignore
irrelevant stimuli. Little is known about its typical and atypical development in early …

Objective Nearly half of children with intellectual disability (ID) have comorbid affective
disorders. These problems are chronic if left untreated and can significantly impact upon …

Background Recent advances in understanding molecular and synaptic mechanisms of
intellectual disabilities (ID) in fragile X syndrome (FXS) and Down syndrome (DS) through …