The rcdk and cluster R packages applied to drug candidate selection
A Voicu, N Duteanu, M Voicu, D Vlad… - Journal of …, 2020 - Springer
The aim of this article is to show how thevpower of statistics and cheminformatics can be
combined, in R, using two packages: rcdk and cluster. We describe the role of clustering …
combined, in R, using two packages: rcdk and cluster. We describe the role of clustering …
3-Pyridinylidene derivatives of chemically modified lupane and ursane triterpenes as promising anticancer agents by targeting apoptosis
O Kazakova, C Șoica, M Babaev, A Petrova… - International Journal of …, 2021 - mdpi.com
Cancer persists as a global challenge due to the extent to which conventional anticancer
therapies pose high risks counterbalanced with their therapeutic benefit. Naturally occurring …
therapies pose high risks counterbalanced with their therapeutic benefit. Naturally occurring …
Design, Synthesis and Biological Activity Evaluation of S-Substituted 1H-5-Mercapto-1,2,4-Triazole Derivatives as Antiproliferative Agents in Colorectal Cancer
Colon cancer is a widespread pathology with complex biochemical etiology based on a
significant number of intracellular signaling pathways that play important roles in …
significant number of intracellular signaling pathways that play important roles in …
Expression of E-cadherin in lung carcinoma, other than those with small cells (NSCLC).
ML Grigoraş, TS Arghirescu, R Folescu… - Romanian Journal of …, 2017 - europepmc.org
It was suggested that the decrease and/or loss of E-cadherin expression in non-small cell
lung cancer (NSCLC) is responsible for the development of the malignant phenotype …
lung cancer (NSCLC) is responsible for the development of the malignant phenotype …
Construction of a novel bispecific fusion protein to enhance targeting for pancreatic cancer imaging
Early detection and diagnosis are the most important endeavors for reducing associated
morbidity and mortality of pancreatic ductal adenocarcinoma (PDAC). Develo** molecular …
morbidity and mortality of pancreatic ductal adenocarcinoma (PDAC). Develo** molecular …
[PDF][PDF] S, oica
O Kazakova - Int. J. Mol. Sci, 2021 - academia.edu
Cancer persists as a global challenge due to the extent to which conventional anticancer
therapies pose high risks counterbalanced with their therapeutic benefit. Naturally occurring …
therapies pose high risks counterbalanced with their therapeutic benefit. Naturally occurring …
Synthesis, Cytotoxic Activity and Molecular Docking Studies of New Condensed Thieno[2,3-d]Pyrimidines as Antitumor Agents
A series of twenty molecules based on thienopyrimidine nucleus fused with 5-, 6-, and 7-
membered lactam rings as well as triazole were synthesized via 4-step reactions. The target …
membered lactam rings as well as triazole were synthesized via 4-step reactions. The target …