The process of cell division plays a vital role in cancer progression. Cell proliferation and
error-free chromosomes segregation during mitosis are central events in life cycle. Mistakes …

Since discovery of the centromere-specific histone H3 variant CENP-A, centromeres have
come to be defined as chromatin structures that establish the assembly site for the complex …

Aurora B, a member of the Aurora family of serine/threonine protein kinases, is a key player
in chromosome segregation. As part of a macromolecular complex known as the …

The centromere proteins (CENPs), a critical mitosis-related protein complexes, are involved
in the kinetochore assembly and chromosome segregation. In this study, we identified that …

The multiprotein kinetochore complex must assemble at a specific site on each chromosome
to achieve accurate chromosome segregation. Defining the nature of the DNA-protein …

Faithful chromosome segregation in all eukaryotes relies on centromeres, the chromosomal
sites that recruit kinetochore proteins and mediate spindle attachment during cell division …

The propagation of all organisms depends on the accurate and orderly segregation of
chromosomes in mitosis and meiosis. Budding yeast has long served as an outstanding …

The kinetochore forms a dynamic interface with microtubules from the mitotic spindle during
mitosis. The Ndc80 complex acts as the key microtubule‐binding complex at kinetochores …

This article discusses the advances made in epigenetic research using the model organism
fission yeast Schizosaccharomyces pombe. S. pombe has been used for epigenetic …

CENP-A acts as an important epigenetic marker for kinetochore specification. However, the
mechanisms by which CENP-A is incorporated into centromeres and the structural basis for …