Cell biology emerges from spatiotemporally coordinated molecular processes. Recent
advances in live-cell microscopy, fueled by a surge in optical, molecular, and computational …

Rapid, high-resolution volumetric imaging without moving heavy objectives or disturbing
delicate samples remains challenging. Pupil-matched remote focusing offers a promising …

Superresolution tools, such as PALM and STORM, provide nanoscale localization accuracy
by relying on rare photophysical events, limiting these methods to static samples. By …

In crowded microenvironments, migrating cells must find or make a path. Amoeboid cells are
thought to find a path by deforming their bodies to squeeze through tight spaces. Yet, some …

Fluorescence microscopy has revolutionized biological research by enabling the
visualization of subcellular structures at high resolution. With the increasing complexity and …

Biological processes, though often imaged and visualized in two dimensions, inherently
occur in at least three-dimensional space. As time-resolved volumetric imaging becomes …

SpinX, an AI-guided spindle tracking software, allows the 3-dimensional (3D) tracking of
metaphase spindle movements in mammalian cells. Using over 900 images of dividing cells …

Volumetric subcellular imaging has long been essential for studying structures and
dynamics in cells and tissues. However, due to limited imaging speed and depth of field, it …

Uncovering fine‐grained phenotypes of live cell dynamics is pivotal for a comprehensive
understanding of the heterogeneity in healthy and diseased biological processes. However …

The latest high-resolution 3D live-cell imaging technology, lattice light-sheet microscopy
(LLSM), has successfully tracked the dynamics of microtubule growth throughout the entire …