The liver is the sixth most common site of primary cancer in humans, and generally arises in
a background of cirrhosis and inflammation. Moreover, the liver is frequently colonized by …

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease, with an
estimated rising prevalence, in concert with the epidemics of obesity and type 2 diabetes …

Hepatocellular carcinoma (HCC) is an increasing burden on global public health and is
associated with enhanced lipogenesis, fatty acid uptake, and lipid metabolic …

Nonalcoholic Fatty Liver Disease (NAFLD) represents the leading cause of liver disease in
developed countries but its diffusion is currently also emerging in Asian countries, in South …

Lipid metabolic reprogramming plays a pivotal role in hepatocellular carcinoma (HCC)
development, but the underlying mechanisms are incompletely characterized. Long chain …

Hepatocellular carcinoma (HCC) is a common cancer worldwide that primarily develops in
cirrhosis resulting from chronic infection by hepatitis B virus and hepatitis C virus, alcoholic …

BACKGROUND & AIMS: De novo lipogenesis is believed to be involved in oncogenesis. We
investigated the role of aberrant lipid biosynthesis in the pathogenesis of human …

Metabolic reprogramming is critically involved in the development and progression of
cancer. In particular, lipid metabolism has been investigated as a source of energy, micro …

Metabolic reprogramming for adaptation to the local environment has been recognized as a
hallmark of cancer. Although alterations in fatty acid (FA) metabolism in cancer cells have …

Hepatocellular carcinoma (HCC) is a primary malignancy of the liver with a high worldwide
prevalence and poor prognosis. Researches are urgently needed on its molecular …