Navigating Available Treatment Options for Carbapenem-Resistant Acinetobacter baumannii-calcoaceticus Complex Infections

RK Shields, DL Paterson… - Clinical Infectious …, 2023 - academic.oup.com
Carbapenem-resistant Acinetobacter baumannii-calcoaceticus complex (CRAB) is one of
the top-priority pathogens for new antibiotic development. Unlike other antibiotic-resistant …

Understanding bacterial pathogenicity: a closer look at the journey of harmful microbes

J Soni, S Sinha, R Pandey - Frontiers in Microbiology, 2024 - frontiersin.org
Bacteria are the most prevalent form of microorganisms and are classified into two
categories based on their mode of existence: intracellular and extracellular. While most …

A novel antibiotic class targeting the lipopolysaccharide transporter

C Zampaloni, P Mattei, K Bleicher, L Winther, C Thäte… - Nature, 2024 - nature.com
Carbapenem-resistant Acinetobacter baumannii (CRAB) has emerged as a major global
pathogen with limited treatment options. No new antibiotic chemical class with activity …

[HTML][HTML] Burden of infectious diseases and bacterial antimicrobial resistance in China: a systematic analysis for the global burden of disease study 2019

C Zhang, X Fu, Y Liu, H Zhao, G Wang - The Lancet Regional Health …, 2024 - thelancet.com
Background Infectious diseases and antimicrobial resistance (AMR) has become pressing
concerns in China. We aimed to comprehensively investigate the burden of them. Methods …

Acinetobacter baumannii in the critically ill: complex infections get complicated

I Cavallo, A Oliva, R Pages, F Sivori, M Truglio… - Frontiers in …, 2023 - frontiersin.org
Acinetobacter baumannii is increasingly associated with various epidemics, representing a
serious concern due to the broad level of antimicrobial resistance and clinical …

Serratia marcescens antibiotic resistance mechanisms of an opportunistic pathogen: a literature review

F Tavares-Carreon, K De Anda-Mora, IC Rojas-Barrera… - PeerJ, 2023 - peerj.com
Serratia marcescens is a ubiquitous bacterium from order Enterobacterales displaying a
high genetic plasticity that allows it to adapt and persist in multiple niches including soil …

Guidelines for the diagnosis, treatment, prevention and control of infections caused by carbapenem-resistant gram-negative bacilli

M Zeng, J **a, Z Zong, Y Shi, Y Ni, F Hu, Y Chen… - Journal of Microbiology …, 2023 - Elsevier
The dissemination of carbapenem-resistant Gram-negative bacilli (CRGNB) is a global
public health issue. CRGNB isolates are usually extensively drug-resistant or pandrug …

Carbapenem-resistant Acinetobacter baumannii: A challenge in the intensive care unit

Y Jiang, Y Ding, Y Wei, C Jian, J Liu… - Frontiers in microbiology, 2022 - frontiersin.org
Carbapenem-resistant Acinetobacter baumannii (CRAB) has become one of the leading
causes of healthcare-associated infections globally, particularly in intensive care units …

Clinical challenges treating Stenotrophomonas maltophilia infections: an update

MF Mojica, R Humphries, JJ Lipuma… - JAC-antimicrobial …, 2022 - academic.oup.com
Stenotrophomonas maltophilia is a non-fermenting, Gram-negative bacillus that has
emerged as an opportunistic nosocomial pathogen. Its intrinsic multidrug resistance makes …

[PDF][PDF] Therapeutic uses and spectrum of cephalosporin generations

I Karunarathna, P Gunasena, T Hapuarachchi… - 2024 - researchgate.net
Cephalosporins are a class of β-lactam antimicrobials employed in treating a wide array of
infections caused by both gram-positive and gram-negative bacteria. The five generations of …