Caffeine as a factor influencing the functioning of the human body—friend or foe?
Nowadays, caffeine is one of the most commonly consumed substances, which presents in
many plants and products. It has both positive and negative effects on the human body, and …
many plants and products. It has both positive and negative effects on the human body, and …
Metabolomics: small molecules that matter more
BC Muthubharathi, T Gowripriya, K Balamurugan - Molecular omics, 2021 - pubs.rsc.org
Metabolomics, an analytical study with high-throughput profiling, helps to understand
interactions within a biological system. Small molecules, called metabolites or metabolomes …
interactions within a biological system. Small molecules, called metabolites or metabolomes …
Comprehensive metabolic profiling of Parkinson's disease by liquid chromatography-mass spectrometry
Background Parkinson's disease (PD) is a prevalent neurological disease in the elderly with
increasing morbidity and mortality. Despite enormous efforts, rapid and accurate diagnosis …
increasing morbidity and mortality. Despite enormous efforts, rapid and accurate diagnosis …
The effect of caffeine on the risk and progression of Parkinson's disease: A meta-analysis
CT Hong, L Chan, CH Bai - Nutrients, 2020 - mdpi.com
Coffee and caffeine are speculated to be associated with the reduced risk of Parkinson's
disease (PD). The present study aimed to investigate the disease-modifying potential of …
disease (PD). The present study aimed to investigate the disease-modifying potential of …
Prediction and collection of protein–metabolite interactions
Interactions between proteins and small molecule metabolites play vital roles in regulating
protein functions and controlling various cellular processes. The activities of metabolic …
protein functions and controlling various cellular processes. The activities of metabolic …
A metabolic profile of polyamines in parkinson disease: A promising biomarker
S Saiki, Y Sasazawa, M Fujimaki… - Annals of …, 2019 - Wiley Online Library
Objective Aging is the highest risk factor for Parkinson disease (PD). Under physiological
conditions, spermidine and spermine experimentally enhance longevity via autophagy …
conditions, spermidine and spermine experimentally enhance longevity via autophagy …
Caffeine synthesis and its mechanism and application by microbial degradation, A review
Z Lin, J Wei, Y Hu, D Pi, M Jiang, T Lang - Foods, 2023 - mdpi.com
Caffeine is a metabolite derived from purine nucleotides, typically accounting for 2–5% of
the dry weight of tea and 1–2% of the dry weight of coffee. In the tea and coffee plants, the …
the dry weight of tea and 1–2% of the dry weight of coffee. In the tea and coffee plants, the …
[HTML][HTML] Recent evidence in epigenomics and proteomics biomarkers for early and minimally invasive diagnosis of Alzheimer's and Parkinson's diseases
S Mayo, J Benito-León, C Peña-Bautista… - Current …, 2021 - ncbi.nlm.nih.gov
Background: Alzheimer's (AD) and Parkinson's diseases (PD) show deposits of improperly
folded modified proteins. Protein expression mechanisms are involved since the early …
folded modified proteins. Protein expression mechanisms are involved since the early …
Identification of metabolites reproducibly associated with Parkinson's Disease via meta-analysis and computational modelling
X Luo, Y Liu, A Balck, C Klein, RMT Fleming - npj Parkinson's Disease, 2024 - nature.com
Many studies have reported metabolomic analysis of different bio-specimens from
Parkinson's disease (PD) patients. However, inconsistencies in reported metabolite …
Parkinson's disease (PD) patients. However, inconsistencies in reported metabolite …
Association of caffeine and related analytes with resistance to Parkinson disease among LRRK2 mutation carriers: A metabolomic study
GF Crotty, R Maciuca, EA Macklin, J Wang… - Neurology, 2020 - AAN Enterprises
Objective To identify markers of resistance to develo** Parkinson disease (PD) among
LRRK2 mutation carriers (LRRK2+), we carried out metabolomic profiling in individuals with …
LRRK2 mutation carriers (LRRK2+), we carried out metabolomic profiling in individuals with …