Smart contact lenses as wearable ophthalmic devices for disease monitoring and health management

H Seo, WG Chung, YW Kwon, S Kim, YM Hong… - Chemical …, 2023 - ACS Publications
The eye contains a complex network of physiological information and biomarkers for
monitoring disease and managing health, and ocular devices can be used to effectively …

Illuminating the brain: advances and perspectives in optoelectronics for neural activity monitoring and modulation

S Xu, M Momin, S Ahmed, A Hossain… - Advanced …, 2023 - Wiley Online Library
Optogenetic modulation of brain neural activity that combines optical and electrical modes in
a unitary neural system has recently gained robust momentum. Controlling illumination …

Evolution of adaptive optics retinal imaging

DR Williams, SA Burns, DT Miller… - Biomedical Optics …, 2023 - opg.optica.org
This review describes the progress that has been achieved since adaptive optics (AO) was
incorporated into the ophthalmoscope a quarter of a century ago, transforming our ability to …

Twenty-five years of clinical applications using adaptive optics ophthalmoscopy

JIW Morgan, TYP Chui, K Grieve - Biomedical Optics Express, 2022 - opg.optica.org
Twenty-five years ago, adaptive optics (AO) was combined with fundus photography,
thereby initiating a new era in the field of ophthalmic imaging. Since that time, clinical …

OCT angiography and its retinal biomarkers

TT Hormel, Y Jia - Biomedical Optics Express, 2023 - opg.optica.org
Optical coherence tomography angiography (OCTA) is a high-resolution, depth-resolved
imaging modality with important applications in ophthalmic practice. An extension of …

Ultrahigh-speed multimodal adaptive optics system for microscopic structural and functional imaging of the human retina

Z Liu, F Zhang, K Zucca, A Agrawal… - Biomedical optics …, 2022 - opg.optica.org
We describe the design and performance of a multimodal and multifunctional adaptive
optics (AO) system that combines scanning laser ophthalmoscopy (SLO) and optical …

Targeting Relevant HDACs to Support the Survival of Cone Photoreceptors in Inherited Retinal Diseases: Identification of a Potent Pharmacological Tool with In Vitro …

G Carullo, N Orsini, I Piano, L Pozzetti… - Journal of Medicinal …, 2024 - ACS Publications
Inherited retinal diseases, which include retinitis pigmentosa, are a family of genetic
disorders characterized by gradual rod-cone degeneration and vision loss, without effective …

[HTML][HTML] Adaptive optics imaging in inherited retinal diseases: A sco** review of the clinical literature

AC Britten-Jones, L Thai, JPM Flanagan… - Survey of …, 2024 - Elsevier
Adaptive optics (AO) imaging enables direct, objective assessments of retinal cells.
Applications of AO show great promise in advancing our understanding of the etiology of …

Structural view of G protein-coupled receptor signaling in the retinal rod outer segment

S Gulati, K Palczewski - Trends in biochemical sciences, 2023 - cell.com
Visual phototransduction is the most extensively studied G protein-coupled receptor (GPCR)
signaling pathway because of its quantifiable stimulus, non-redundancy of genes, and …

Human cone elongation responses can be explained by photoactivated cone opsin and membrane swelling and osmotic response to phosphate produced by RGS9 …

VP Pandiyan, PT Nguyen… - Proceedings of the …, 2022 - National Acad Sciences
Human cone outer segment (COS) length changes in response to stimuli bleaching up to
99% of L-and M-cone opsins were measured with high resolution, phase-resolved optical …