Epithelial–mesenchymal transitions (EMTs) are an important mechanism for reorganizing
germ layers and tissues during embryonic development. They have both a morphogenic …

Polarized cell movements shape the major features of the vertebrate body plan during
development. The head-to-tail body axis of vertebrates is elongated in embryonic stages by …

Planar cell polarity (PCP) proteins form polarized cortical domains that govern polarity of
external structures such as hairs and cilia in both vertebrate and invertebrate epithelia. The …

Neural-tube closure is a critical step of embryogenesis, and its failure causes serious birth
defects. Coordination of two morphogenetic processes—convergent extension and neural …

Evaluation of the central nervous system (CNS) in the develo** mouse presents unique
challenges, given the complexity of ontogenesis, marked structural reorganization over very …

During development, vertebrate embryos undergo dramatic changes in shape. The
lengthening and narrowing of a field of cells, termed convergent extension, contributes to a …

The cells of many embryonic tissues actively narrow in one dimension (convergence) and
lengthen in the perpendicular dimension (extension). Convergence and extension are …

The planar cell polarity (PCP) signaling pathway governs collective cell movements during
vertebrate embryogenesis, and certain PCP proteins are also implicated in the assembly of …

Development of the Nervous System presents a broad and basic treatment of the
established and evolving principles of neural development as exemplified by key …

During development cells and tissues undergo changes in pattern and form that employ a
wider range of physical mechanisms than at any other time in an organism's life. This book …