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Flavin dependent monooxygenases
MME Huijbers, S Montersino, AH Westphal… - Archives of biochemistry …, 2014 - Elsevier
Flavin-dependent monooxygenases catalyze a wide variety of chemo-, regio-and
enantioselective oxygenation reactions. As such, they are involved in key biological …
enantioselective oxygenation reactions. As such, they are involved in key biological …
[HTML][HTML] Oxidation and reduction of actin: Origin, impact in vitro and functional consequences in vivo
C Rouyère, T Serrano, S Frémont, A Echard - European journal of cell …, 2022 - Elsevier
Actin is among the most abundant proteins in eukaryotic cells and assembles into dynamic
filamentous networks regulated by many actin binding proteins. The actin cytoskeleton must …
filamentous networks regulated by many actin binding proteins. The actin cytoskeleton must …
Direct redox regulation of F-actin assembly and disassembly by Mical
Different types of cell behavior, including growth, motility, and navigation, require actin
proteins to assemble into filaments. Here, we describe a biochemical process that was able …
proteins to assemble into filaments. Here, we describe a biochemical process that was able …
Metastasis: cancer cell's escape from oxidative stress
According to a “canonical” view, reactive oxygen species (ROS) positively contribute, in
different ways, to carcinogenesis and to malignant progression of tumor cells: they drive …
different ways, to carcinogenesis and to malignant progression of tumor cells: they drive …
MICAL-mediated oxidation of actin and its effects on cytoskeletal and cellular dynamics
S Rajan, JR Terman, E Reisler - Frontiers in cell and developmental …, 2023 - frontiersin.org
Actin and its dynamic structural remodelings are involved in multiple cellular functions,
including maintaining cell shape and integrity, cytokinesis, motility, navigation, and muscle …
including maintaining cell shape and integrity, cytokinesis, motility, navigation, and muscle …
Oxidation of F-actin controls the terminal steps of cytokinesis
Cytokinetic abscission, the terminal step of cell division, crucially depends on the local
constriction of ESCRT-III helices after cytoskeleton disassembly. While the microtubules of …
constriction of ESCRT-III helices after cytoskeleton disassembly. While the microtubules of …
Glucocorticoids, genes and brain function
GR Juszczak, AM Stankiewicz - Progress in Neuro-Psychopharmacology …, 2018 - Elsevier
The identification of key genes in transcriptomic data constitutes a huge challenge. Our
review of microarray reports revealed 88 genes whose transcription is consistently regulated …
review of microarray reports revealed 88 genes whose transcription is consistently regulated …
Mical links semaphorins to F-actin disassembly
How instructive cues present on the cell surface have their precise effects on the actin
cytoskeleton is poorly understood. Semaphorins are one of the largest families of these …
cytoskeleton is poorly understood. Semaphorins are one of the largest families of these …
Toward rational protein crystallization: A Web server for the design of crystallizable protein variants
Growing well‐diffracting crystals constitutes a serious bottleneck in structural biology. A
recently proposed crystallization methodology for “stubborn crystallizers” is to engineer …
recently proposed crystallization methodology for “stubborn crystallizers” is to engineer …
Oxidants in physiological processes
UG Knaus - Reactive oxygen species: Network pharmacology and …, 2021 - Springer
A number of diseases and conditions have been associated with prolonged or persistent
exposure to non-physiological levels of reactive oxygen species (ROS). Similarly, ROS …
exposure to non-physiological levels of reactive oxygen species (ROS). Similarly, ROS …