Bidirectional microglia–neuron communication in health and disease

Z Szepesi, O Manouchehrian, S Bachiller… - Frontiers in cellular …, 2018 - frontiersin.org
Microglia are ramified cells that exhibit highly motile processes, which continuously survey
the brain parenchyma and react to any insult to the CNS homeostasis. Although microglia …

[HTML][HTML] Cell-to-cell communication by extracellular vesicles: focus on microglia

RC Paolicelli, G Bergamini, L Rajendran - Neuroscience, 2019 - Elsevier
Extracellular vesicles, including exosomes and microvesicles, are small, nano-to-micrometer
vesicles that are released from cells. While initially observed in immune cells and …

Neuron-glia signaling in synapse elimination

DK Wilton, L Dissing-Olesen… - Annual review of …, 2019 - annualreviews.org
Maturation of neuronal circuits requires selective elimination of synaptic connections.
Although neuron-intrinsic mechanisms are important in this process, it is increasingly …

Microglia secrete miR-146a-5p-containing exosomes to regulate neurogenesis in depression

C Fan, Y Li, T Lan, W Wang, Y Long, SY Yu - Molecular Therapy, 2022 - cell.com
Enhancing neurogenesis within the hippocampal dentate gyrus (DG) is critical for
maintaining brain development and function in many neurological diseases. However, the …