Schizophrenia is a debilitating mental illness which involves three groups of symptoms, ie,
positive, negative and cognitive, and has major public health implications. According to …

The glutamate and dopamine hypotheses are leading theories of the pathoaetiology of
schizophrenia. Both were initially based on indirect evidence from pharmacological studies …

Although now believed to be two distinct disorders, autism spectrum disorders (ASD) and
schizophrenia spectrum disorders (SSD) share multiple phenotypic similarities and risk …

Schizophrenia is a severe chronic psychiatric illness, characterized by hallucinations and
delusions. Decreased brain volumes have been observed in the disease, although the …

Autoimmune mechanisms causing diverse psychiatric symptoms are increasingly
recognized and brought about a paradigm shift in neuropsychiatry. Identification of …

The discovery of the rapid antidepressant effects of the dissociative anaesthetic ketamine,
an uncompetitive N-Methyl-D-Aspartate receptor antagonist, is arguably the most important …

Diathesis-stress models of schizophrenia and other psychotic disorders have dominated
theorizing about etiology for over three decades. More recently, with advances in our …

This review summarizes evidence of dysregulated reward circuitry function in a range of
neurodevelopmental and psychiatric disorders and genetic syndromes. First, the …

Objective: To report the definitive diagnosis of anti-NMDA receptor (NMDAR) encephalitis in
four Japanese women previously diagnosed with “juvenile acute nonherpetic encephalitis” …

Importance The use of high-field magnetic resonance spectroscopy (MRS) in multiple brain
regions of a large population of human participants facilitates in vivo study of localized or …