Simple Summary Prostate cancer affects men of all racial and ethnic groups and leads to
higher rates of mortality in those belonging to a lower socioeconomic status due to late …

The faithful execution of biological processes requires a precise and carefully orchestrated
set of steps that depend on the proper spatial and temporal expression of genes. Here we …

The transferability and clinical value of genetic risk scores (GRSs) across populations
remain limited due to an imbalance in genetic studies across ancestrally diverse …

Richter syndrome (RS) derives from the rare transformation of chronic lymphocytic leukemia
(CLL) into an aggressive lymphoma, most commonly of the diffuse large B cell lymphoma …

Comparisons of DNA from archaic and modern humans show that these groups interbred,
and in some cases received an evolutionary advantage from doing so. This process …

Neurodevelopmental disorders (NDDs) result from impaired development and functioning of
the brain. Here, we identify loss-of-function (LoF) variation in ZFHX3 as a cause for …

We conducted meta-analyses of genome-wide association studies for atrial fibrillation (AF)
in participants from five community-based cohorts. Meta-analyses of 896 prevalent (15,768 …

Although prostate cancer is the most common malignancy to affect men in the Western
world, the molecular mechanisms underlying its development and progression remain …

Objectives Long non-coding RNAs (lncRNA) have been shown to play important roles in the
development and progression of cancer. However, functional lncRNAs and their …

Quantitative and structural genetic alterations cause the development and progression of
prostate cancer. A number of genes have been implicated in prostate cancer by genetic …