Stroke is a heterogeneous syndrome, and determining risk factors and treatment depends
on the specific pathogenesis of stroke. Risk factors for stroke can be categorized as …

Since the discovery of sickle cell disease (SCD) in 1910, enormous strides have been made
in the elucidation of the pathogenesis of its protean complications, which has inspired recent …

Purpose—Much has transpired since the last scientific statement on pediatric stroke was
published 10 years ago. Although stroke has long been recognized as an adult health …

Background Silent cerebral infarcts are the most common neurologic injury in children with
sickle cell anemia and are associated with the recurrence of an infarct (stroke or silent …

Silent cerebral infarct (SCI) is the most common form of neurologic disease in children with
sickle cell anemia (SCA). SCI is defined as abnormal magnetic resonance imaging (MRI) of …

Red cell transfusion remains a critical component of care for acute and chronic
complications of sickle cell disease. Randomized clinical trials demonstrated the benefits of …

Over the past 40 years, public health measures such as universal newborn screening,
penicillin prophylaxis, vaccinations, and hydroxyurea therapy have led to an impressive …

Children with sickle cell disease (SCD) and strokes receive blood transfusion therapy for
secondary stroke prevention; despite this, approximately 20% experience second overt …

Silent cerebral infarcts (SCIs) are associated with cognitive impairment in sickle cell anemia
(SCA). SCI risk factors include low hemoglobin and elevated systolic blood pressure; …

Education is one of the most important aspects of human resource development. Poor
school performance not only results in the child having a low self-esteem, but also causes …