Neuroinflammation and oxidative stress in the pathogenesis of autism spectrum disorder

N Usui, H Kobayashi, S Shimada - International journal of molecular …, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder (NDD) characterized by
impairments in social communication, repetitive behaviors, restricted interests, and …

Autism spectrum disorder: pathogenesis, biomarker, and intervention therapy

H Zhuang, Z Liang, G Ma, A Qureshi, X Ran… - MedComm, 2024 - Wiley Online Library
Autism spectrum disorder (ASD) has become a common neurodevelopmental disorder. The
heterogeneity of ASD poses great challenges for its research and clinical translation. On the …

[HTML][HTML] Developmental neurotoxic effects of bisphenol A and its derivatives in Drosophila melanogaster

J Wang, C Wu, X Zhang, Y Song, B Wang… - Ecotoxicology and …, 2023 - Elsevier
As a result of the ban on bisphenol A (BPA), a hormone disruptor with developmental
neurotoxicity, several BPA derivatives (BPs) have been widely used in industrial production …

Between dysbiosis, maternal immune activation and autism: Is there a common pathway?

M Suprunowicz, N Tomaszek, A Urbaniak… - Nutrients, 2024 - mdpi.com
Autism spectrum disorder (ASD) is a neuropsychiatric condition characterized by impaired
social interactions and repetitive stereotyped behaviors. Growing evidence highlights an …

Induced pluripotent stem cells and organoids in advancing neuropathology research and therapies

DB Pazzin, TTR Previato, JI Budelon Gonçalves… - Cells, 2024 - mdpi.com
This review delves into the groundbreaking impact of induced pluripotent stem cells (iPSCs)
and three-dimensional organoid models in propelling forward neuropathology research …

The role of parvalbumin interneurons in autism spectrum disorder

Y Yao, Q Li - Journal of Neuroscience Research, 2024 - Wiley Online Library
As an important subtype of GABAergic interneurons, parvalbumin (PV) interneurons play a
critical role in regulating cortical circuits and neural networks. Abnormalities in the …

Effects and microbiota changes following oral lyophilized fecal microbiota transplantation in children with autism spectrum disorder

Y Li, P **ao, R Cao, J Le, Q Xu, F **ao, L Ye… - Frontiers in …, 2024 - frontiersin.org
Background and purpose Autism spectrum disorder (ASD) is a group of heterogeneous
neurodevelopmental disorders that is characterized by core features in social …

Inferring the genetic effects of serum homocysteine and vitamin B levels on autism spectral disorder through Mendelian randomization

T **, W Huang, Q Pang, Z He, L Yuan, H Zhang… - European Journal of …, 2024 - Springer
Purpose The previous studies have suggested that serum homocysteine (Hcy) and vitamin B
levels are potentially related to autism spectrum disorder (ASD). However, the causality …

A pH-Dependent Coarse-Grained Model for Disordered Proteins: Histidine Interactions Modulate Conformational Ensembles

R Calinsky, Y Levy - The Journal of Physical Chemistry Letters, 2024 - ACS Publications
Histidine (His) presents a unique challenge for modeling disordered protein conformations,
as it is versatile and occurs in both the neutral (His0) and positively charged (His+) states …

Semaphorin 3A influences neuronal processes that are altered in patients with autism spectrum disorder: Potential diagnostic and therapeutic implications

C Matrone, G Ferretti - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
Autism spectrum disorder (ASD) is a pervasive disorder that most frequently manifests in
early childhood and lasts for their entire lifespan. Several behavioural traits characterise the …