Sperm selection for ICSI: do we have a winner?

D Baldini, D Ferri, GM Baldini, D Lot, A Catino… - Cells, 2021 - mdpi.com
In assisted reproductive technology (ART), the aim of sperm cells' preparation is to select
competent spermatozoa with the highest fertilization potential and in this context, the …

Molecular basis of human sperm capacitation

LC Puga Molina, GM Luque, PA Balestrini… - Frontiers in cell and …, 2018 - frontiersin.org
In the early 1950s, Austin and Chang independently described the changes that are
required for the sperm to fertilize oocytes in vivo. These changes were originally grouped …

Novel techniques of sperm selection for improving IVF and ICSI outcomes

I Oseguera-López, S Ruiz-Díaz… - Frontiers in cell and …, 2019 - frontiersin.org
Almost 50% of the infertility cases are due to male factors. Assisted reproductive
technologies (ARTs) allow to overcome the incapacity of these patients' spermatozoa to …

Sperm migration, selection, survival, and fertilizing ability in the mammalian oviduct

C Mahé, AM Zlotkowska, K Reynaud… - Biology of …, 2021 - academic.oup.com
In vitro fertilization (IVF) gives rise to embryos in a number of mammalian species and is
currently widely used for assisted reproduction in humans and for genetic purposes in cattle …

Simulating nature in sperm selection for assisted reproduction

ETY Leung, CL Lee, X Tian, KKW Lam, RHW Li… - Nature Reviews …, 2022 - nature.com
Sperm selection in the female reproductive tract (FRT) is sophisticated. Only about 1,000
sperm out of millions in an ejaculate reach the fallopian tube and thus have a chance of …

Microfluidic in-vitro fertilization technologies: Transforming the future of human reproduction

Y Fang, R Wu, JM Lee, LHM Chan, KYJ Chan - TrAC Trends in Analytical …, 2023 - Elsevier
The field of assisted reproductive technology (ART) has seen constant improvement and
advancement targeted towards optimal development of the embryos in vitro to improve …

Odorant and taste receptors in sperm chemotaxis and cryopreservation: roles and implications in sperm capacitation, motility and fertility

MA Ali, Y Wang, Z Qin, X Yuan, Y Zhang, C Zeng - Genes, 2021 - mdpi.com
Sperm chemotaxis, which guide sperm toward oocyte, is tightly associated with sperm
capacitation, motility, and fertility. However, the molecular mechanism of sperm chemotaxis …

Progesterone, spermatozoa and reproduction: An updated review

L Tamburrino, S Marchiani, M Muratori, M Luconi… - Molecular and cellular …, 2020 - Elsevier
The rapid effects of steroids on spermatozoa have been demonstrated for the first time more
than three decades ago. Progesterone (P), which is present throughout the female genital …

Generation of gradients on a microfluidic device: toward a high-throughput investigation of spermatozoa chemotaxis

Y Zhang, RR **ao, T Yin, W Zou, Y Tang, J Ding… - PloS one, 2015 - journals.plos.org
Various research tools have been used for in vitro detection of sperm chemotaxis. However,
they are typically poor in maintenance of gradient stability, not to mention their low efficiency …

Sperm selection by the oviduct: perspectives for male fertility and assisted reproductive technologies

S Soto-Heras, D Sakkas, DJ Miller - Biology of reproduction, 2023 - academic.oup.com
The contribution of sperm to embryogenesis is gaining attention with up to 50% of infertility
cases being attributed to a paternal factor. The traditional methods used in assisted …