Machine intelligence for chemical reaction space

P Schwaller, AC Vaucher, R Laplaza… - Wiley …, 2022 - Wiley Online Library
Discovering new reactions, optimizing their performance, and extending the synthetically
accessible chemical space are critical drivers for major technological advances and more …

Automation and computer-assisted planning for chemical synthesis

Y Shen, JE Borowski, MA Hardy, R Sarpong… - Nature Reviews …, 2021 - nature.com
The molecules of today—the medicines that cure diseases, the agrochemicals that protect
our crops, the materials that make life convenient—are becoming increasingly sophisticated …

[HTML][HTML] Machine learning in chemical engineering: strengths, weaknesses, opportunities, and threats

MR Dobbelaere, PP Plehiers, R Van de Vijver… - Engineering, 2021 - Elsevier
Chemical engineers rely on models for design, research, and daily decision-making, often
with potentially large financial and safety implications. Previous efforts a few decades ago to …

Organic reactivity from mechanism to machine learning

K Jorner, A Tomberg, C Bauer, C Sköld… - Nature Reviews …, 2021 - nature.com
As more data are introduced in the building of models of chemical reactivity, the mechanistic
component can be reduced until 'big data'applications are reached. These methods no …

Machine learning force fields: Recent advances and remaining challenges

I Poltavsky, A Tkatchenko - The journal of physical chemistry …, 2021 - ACS Publications
In chemistry and physics, machine learning (ML) methods promise transformative impacts by
advancing modeling and improving our understanding of complex molecules and materials …

Inferring experimental procedures from text-based representations of chemical reactions

AC Vaucher, P Schwaller, J Geluykens, VH Nair… - Nature …, 2021 - nature.com
The experimental execution of chemical reactions is a context-dependent and time-
consuming process, often solved using the experience collected over multiple decades of …

Into the unknown: how computation can help explore uncharted material space

AM Mroz, V Posligua, A Tarzia… - Journal of the …, 2022 - ACS Publications
Novel functional materials are urgently needed to help combat the major global challenges
facing humanity, such as climate change and resource scarcity. Yet, the traditional …

Predicting reaction conditions from limited data through active transfer learning

E Shim, JA Kammeraad, Z Xu, A Tewari, T Cernak… - Chemical …, 2022 - pubs.rsc.org
Transfer and active learning have the potential to accelerate the development of new
chemical reactions, using prior data and new experiments to inform models that adapt to the …

Intensification of catalytic reactors: a synergic effort of multiscale modeling, machine learning and additive manufacturing

M Bracconi - Chemical Engineering and Processing-Process …, 2022 - Elsevier
The intensification of catalytic reactors is expected to play a crucial role to address the
challenges that the chemical industry is facing in the transition to more sustainable …

A review on artificial intelligence enabled design, synthesis, and process optimization of chemical products for industry 4.0

C He, C Zhang, T Bian, K Jiao, W Su, KJ Wu, A Su - Processes, 2023 - mdpi.com
With the development of Industry 4.0, artificial intelligence (AI) is gaining increasing attention
for its performance in solving particularly complex problems in industrial chemistry and …